Slusarek Anna, Hamaide Annick, Lefebvre Michaël, Heimann Marianne, Billen Frédéric, Bolen Géraldine
Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.
Centre vétérinaire de Spécialistes Caladrius, Wavre, Belgium.
Front Vet Sci. 2025 Sep 4;12:1633591. doi: 10.3389/fvets.2025.1633591. eCollection 2025.
To describe the computed tomographic (CT) features of neoplastic and inflammatory laryngeal masses. The authors hypothesized that specific CT features may help differentiate between these two origins and that regional lymph nodes would be larger in cases of laryngeal neoplasia.
Medical records from two veterinary referral hospitals were screened for dogs diagnosed with either an inflammatory or neoplastic laryngeal mass who underwent CT scans of the neck. Information retrieved from medical records included signalment, physical examination findings, CT scan findings, and definitive diagnosis of the laryngeal mass based on cytological or histopathological results.
Four dogs had laboratory reports compatible with a malignant neoplasia and three with an inflammatory process. The shape of the mass was defined as "ovoid" in all neoplastic masses and as "thickening" in cases of inflammatory processes. Masses were of various sizes (median length: 42 mm, range: 26-82 mm) and either unilateral (1/4 and 2/3 of neoplastic and inflammatory masses respectively) or bilateral. They were described as mineralized (1/4 and 1/3) and as having either an internal (1/4), external (2/4) growth pattern or both (1/4, 3/3). All masses had ill-defined margins and showed heterogeneous contrast enhancement. Two neoplastic and two inflammatory masses had a cavitary aspect. All but one case were associated with regional lymphadenopathy. Thyroid cartilage destruction was observed with two neoplastic and two inflammatory masses.
This case series describes CT features of laryngeal masses. The shape of the laryngeal mass may assist in determining its nature, inflammatory process was defined as "thickening" of the larynx and neoplasia as "ovoid"-shaped, whereas other studied features were inconsistently observed in both neoplastic and inflammatory conditions.
描述喉肿瘤性和炎症性肿块的计算机断层扫描（CT）特征。作者推测特定的CT特征可能有助于区分这两种病变起源，并且喉肿瘤病例中的区域淋巴结会更大。
对两家兽医转诊医院的病历进行筛查，筛选对象为诊断患有炎症性或肿瘤性喉肿块并接受颈部CT扫描的犬只。从病历中获取的信息包括信号、体格检查结果、CT扫描结果以及基于细胞学或组织病理学结果的喉肿块确诊诊断。
四只犬的实验室报告符合恶性肿瘤，三只犬符合炎症过程。在所有肿瘤性肿块中，肿块形状被定义为“椭圆形”，在炎症性病变中被定义为“增厚”。肿块大小各异（中位数长度：42毫米，范围：26 - 82毫米），且要么为单侧（肿瘤性和炎症性肿块分别占1/4和2/3），要么为双侧。它们被描述为有矿化（1/4和1/3），并且具有内部（1/4）、外部（2/4）生长模式或两者皆有（1/4，3/3）。所有肿块边界不清，对比增强不均匀。两个肿瘤性肿块和两个炎症性肿块有空洞样表现。除一例之外，所有病例均伴有区域淋巴结病。在两个肿瘤性肿块和两个炎症性肿块中观察到甲状腺软骨破坏。
本病例系列描述了喉肿块的CT特征。喉肿块的形状可能有助于确定其性质，炎症过程被定义为喉部“增厚”，肿瘤为“椭圆形”，而在肿瘤性和炎症性病变中其他研究特征的观察结果并不一致。
