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早期妊娠中酷似恶性肿瘤的宫颈蜕膜变性:

Cervical Deciduosis in Early Pregnancy Mimicking Malignancy: .

作者信息

Sebastian Ajit, Salih Nada, Jose Shiby, Al Dughaishi Tamima, Gowri Vaidyanathan

机构信息

Department of Obstetrics & Gynaecology, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman.

Department of Obstetrics & Gynaecology, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.

出版信息

Sultan Qaboos Univ Med J. 2025 May 2;25(1):547-551. doi: 10.18295/2075-0528.2870. eCollection 2025.

DOI:10.18295/2075-0528.2870
PMID:40979597
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12445304/
Abstract

Deciduosis is a benign condition characterised by the transformation of subepithelial connective tissue into decidual-like cells, typically occurring in response to hormonal changes during pregnancy. Although benign, cervical deciduosis may macroscopically resemble malignant lesions, leading to diagnostic uncertainty. This report presents two cases of cervical deciduosis diagnosed in early pregnancy. Both patients presented with first-trimester vaginal bleeding, and speculum examination revealed extensive wart-like lesions covering the cervix. Histopathological examination of cervical biopsies confirmed decidual changes. In pregnant women presenting with threatened miscarriage, a thorough local examination and biopsy of atypical cervical lesions are essential to exclude malignancy. As cervical deciduosis is a benign and self-limiting condition, no further treatment is usually required.

摘要

蜕膜样变是一种良性病变,其特征是上皮下结缔组织转化为蜕膜样细胞,通常发生于孕期激素变化时。尽管为良性,但宫颈蜕膜样变在肉眼上可能类似于恶性病变,导致诊断存在不确定性。本报告呈现了两例在孕早期诊断为宫颈蜕膜样变的病例。两名患者均表现为孕早期阴道出血,窥器检查发现宫颈有广泛的疣状病变。宫颈活检的组织病理学检查证实有蜕膜样改变。对于出现先兆流产的孕妇,对非典型宫颈病变进行全面的局部检查和活检对于排除恶性肿瘤至关重要。由于宫颈蜕膜样变是一种良性且自限性的疾病,通常无需进一步治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd3e/12445304/d023adaf308f/squmj_v25_n01_squmj6844-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd3e/12445304/a96b644af277/squmj_v25_n01_squmj6844-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd3e/12445304/d023adaf308f/squmj_v25_n01_squmj6844-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd3e/12445304/a96b644af277/squmj_v25_n01_squmj6844-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd3e/12445304/d023adaf308f/squmj_v25_n01_squmj6844-g002.jpg

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本文引用的文献

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Ectopic Cervical Deciduosis: A Rare Cause of Antepartum Hemorrhage in Mid Trimester.异位宫颈蜕膜样变:孕中期产前出血的罕见原因
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