Riyami Maryam Al, Al Alawi Abdullah, Balushi Hajar Al, Ghafri Raya Al, Mamari Hafsa Al, Al-Aghbari Jamal
Ministry of Health, Muscat, Oman.
Sultan Qaboos University Hospital, University Medical City, Muscat, Oman.
Sultan Qaboos Univ Med J. 2025 May 2;25(1):765-772. doi: 10.18295/2075-0528.2890. eCollection 2025.
Pulmonary embolism (PE) is a potentially fatal condition among hospitalised patients, with a prevalence of approximately 1.0%. PE is associated with high morbidity and mortality. This study aimed to identify patient characteristics and risk factors related to the development, recurrence, and mortality of PE in hospitalised patients at Sultan Qaboos University Hospital (SQUH), Muscat, Oman.
This retrospective cohort study was conducted at SQUH, involving patients diagnosed with PE during admission between January 2015 and December 2019. Data were collected from electronic patient records, including demographic details, comorbidities, risk factors and healthcare outcomes. Pulmonary Embolism Severity Index (PESI) scores were calculated. Statistical analyses were performed to identify predictors of mortality and recurrence of PE.
A total of 192 patients diagnosed with PE were included in this study; 16.7% died during the index admission. Older age, higher PESI scores, central venous access and autoimmune disease were significant independent predictors of inpatient mortality. The recurrence rate of PE was 9.5% during the follow-up period, with no significant association between patient characteristics and recurrence. This study also highlighted the prevalence of risk factors such as reduced mobility, recent hospitalisation, obesity and infection among the cohort.
This research contributes to the knowledge of PE recurrence, mortality and associated risk factors. Hypertension, diabetes and chronic heart failure are common comorbidities in PE patients. Older age, higher PESI scores, central venous access and autoimmune disease were significant predictors of mortality.
肺栓塞(PE)在住院患者中是一种潜在的致命疾病,患病率约为1.0%。PE与高发病率和死亡率相关。本研究旨在确定阿曼马斯喀特苏丹卡布斯大学医院(SQUH)住院患者中与PE发生、复发和死亡相关的患者特征及危险因素。
本回顾性队列研究在SQUH开展,纳入2015年1月至2019年12月住院期间诊断为PE的患者。从电子病历中收集数据,包括人口统计学细节、合并症、危险因素和医疗结局。计算肺栓塞严重程度指数(PESI)评分。进行统计分析以确定PE死亡率和复发的预测因素。
本研究共纳入192例诊断为PE的患者;16.7%在首次住院期间死亡。年龄较大、PESI评分较高、中心静脉置管和自身免疫性疾病是住院死亡率的显著独立预测因素。随访期间PE复发率为9.5%,患者特征与复发之间无显著关联。本研究还强调了该队列中危险因素的普遍性,如活动减少、近期住院、肥胖和感染。
本研究有助于了解PE的复发、死亡率及相关危险因素。高血压、糖尿病和慢性心力衰竭是PE患者常见的合并症。年龄较大、PESI评分较高、中心静脉置管和自身免疫性疾病是死亡率的显著预测因素。