Thylstrup A, Andreasen J O
J Oral Pathol. 1977 Sep;6(5):296-306. doi: 10.1111/j.1600-0714.1977.tb01652.x.
Primary maxillary and mandibular central incisors were experimentally intruded on 13 monkeys, in order to examine changes of the enamel in the permanent successors. To study the effect of removal of the displaced tooth, the left primary incisor was extracted 1 h after the trauma, whereas that on the right was left in the jaw. Six weeks later the animals were sacrificed. Macroscopically, circumscribed areas of opacities on labial enamel were noted. The SEM examination showed that non-affected parts of enamel had reached anatomical form, whereas inhibition studies and microradiographs demonstrated that the maturation process was far from complete. Arrest of enamel maturation was noted as corresponding to the extent of the surface opacity. In the SEM small areas displaying rupture of the surface enamel were seen. No differences were observed either macroscopically or histologically in relation to immediate removal or preservation of the intruded primary incisor.
为了研究恒牙胚中釉质的变化，对13只猴子的上颌和下颌乳中切牙进行了实验性压入。为了研究拔除移位牙的影响，在创伤后1小时拔除左侧乳切牙，而右侧乳切牙则保留在颌骨中。六周后处死动物。肉眼可见，唇面釉质出现局限性混浊区域。扫描电镜检查显示，未受影响的釉质部分已达到解剖形态，而抑制研究和显微放射照片表明，成熟过程远未完成。观察到釉质成熟停滞与表面混浊程度相对应。扫描电镜下可见表面釉质有小面积破裂。在拔除或保留被压入的乳切牙方面，无论是肉眼观察还是组织学观察，均未发现差异。
