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鸽饲养者病中的抗原。

Antigens in pigeon breeders' disease.

作者信息

Edwards J H, Barboriak J J, Fink J N

出版信息

Immunology. 1970 Nov;19(5):729-34.

PMID:4098599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1455654/
Abstract

It has been shown that many pigeon materials contain one or more of four pigeon proteins—pigeon γ-globulin (PGG), pigeon serum albumin (PSA), pigeon β-globulin (PBG) and a protein cross-reacting immunologically with PGG termed XPGG. It is thought that the ability of seemingly unrelated sources of pigeon material, e.g. pigeon droppings, serum, egg yolk and white to react with sera from cases of pigeon breeders' disease is due to the presence of PGG, PSA, PBG or XPGG in these materials. Only in pigeon droppings were important antigens other than PGG, PSA, PBG and XPGG found and it is possible that pigeon droppings are the only `complete' source of antigens concerned with the disease unless specified conditions arise.

摘要

已经表明,许多鸽源材料含有四种鸽蛋白中的一种或多种——鸽γ球蛋白(PGG)、鸽血清白蛋白(PSA)、鸽β球蛋白(PBG)以及一种与PGG发生免疫交叉反应的蛋白,称为XPGG。据认为,看似不相关的鸽源材料,如鸽粪、血清、蛋黄和蛋清,能够与鸽饲养者病患者的血清发生反应,是由于这些材料中存在PGG、PSA、PBG或XPGG。仅在鸽粪中发现了除PGG、PSA、PBG和XPGG之外的重要抗原,并且除非出现特定情况,鸽粪有可能是与该疾病相关的唯一“完整”抗原来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a13c/1455654/2da8c818986b/immunology00370-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a13c/1455654/2da8c818986b/immunology00370-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a13c/1455654/2da8c818986b/immunology00370-0046-a.jpg

相似文献

1
Antigens in pigeon breeders' disease.鸽饲养者病中的抗原。
Immunology. 1970 Nov;19(5):729-34.
2
Antigens in pigeon breeder's disease: isolation of a homogeneous antigen from pigeon dropping extract and its relationship to pigeon serum antigens.养鸽者病中的抗原:从鸽粪提取物中分离出一种纯一抗原及其与鸽血清抗原的关系
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引用本文的文献

1
Protein antigen of bird-related hypersensitivity pneumonitis in pigeon serum and dropping.鸽血清和鸽粪中与鸟类相关的过敏性肺炎的蛋白质抗原。
Respir Res. 2017 Apr 20;18(1):65. doi: 10.1186/s12931-017-0555-4.
2
An enzyme in pigeon droppings, of possible relevance to pigeon breeder's disease.鸽粪中的一种酶,可能与养鸽者病有关。
Clin Exp Immunol. 1972 Feb;10(2):383-9.
3
Extrinsic allergic alveolitis.外源性过敏性肺泡炎

本文引用的文献

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Farmer's lung; a form of pneumoconiosis due to organic dusts.
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Antigenic specificity in a hypersensitivity pneumonitis.超敏性肺炎中的抗原特异性
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Pigeon breeders' disease. A clinical study of a hypersensitivity pneumonitis.鸽饲养者病。一种过敏性肺炎的临床研究。
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Excretion of pigeon serum proteins in pigeon droppings.
Proc Soc Exp Biol Med. 1969 Dec;132(3):907-11. doi: 10.3181/00379727-132-34334.
10
The immunoglobulins: a review.免疫球蛋白:综述
J Clin Pathol. 1969 Mar;22(2):117-31. doi: 10.1136/jcp.22.2.117.