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紫色尿袋综合征:尿路感染的一种罕见表现:病例系列及文献综述

Purple urine bag syndrome: An unusual presentation of urinary tract infection: A case series and literature review.

作者信息

Basehi Mohammed F, Dallak Fatimah H, Darraj Atheer I, Almalki Sultan J

机构信息

Emergency Department, King Fahd Central Hospital, Jazan Health Cluster, Jazan, Saudi Arabia.

Internal Medicine Department, King Fahd Central Hospital, Jazan Health Cluster, Jazan, Saudi Arabia.

出版信息

Medicine (Baltimore). 2025 Sep 19;104(38):e44638. doi: 10.1097/MD.0000000000044638.

DOI:10.1097/MD.0000000000044638
PMID:40988186
Abstract

RATIONALE

Purple urine bag syndrome (PUBS) is a rare but visually alarming condition associated with urinary tract infections (UTIs), typically occurring in debilitated elderly patients with long-term indwelling catheters. Awareness of PUBS is essential, as it can serve as an indicator of underlying infection.

PATIENT CONCERNS

Two elderly male patients presented with striking purple discoloration of their urinary catheter bags. Caregivers expressed concern, although both patients denied fever, dysuria, or suprapubic pain.

DIAGNOSES

PUBS secondary to UTI was diagnosed. Case 1 involved mixed bacterial growth, with risk factors including diabetes mellitus, benign prostatic hyperplasia, immobility, and prolonged catheterization. Case 2 had Candida tropicalis infection, with predisposing factors of stroke-related immobility, constipation, and chronic catheterization.

INTERVENTIONS

Both patients underwent a Foley catheter and urine bag replacement. Case 1 received empirical oral ciprofloxacin, while case 2 required admission, intravenous antifungal therapy, and supportive hydration.

OUTCOMES

Purple discoloration resolved after catheter replacement. Both patients achieved favorable outcomes without recurrence.

LESSONS

While PUBS is typically benign, it reflects underlying UTIs and requires prompt intervention. Early recognition, catheter management, and appropriate antimicrobial therapy are key to preventing complications. Clinician awareness is vital to avoid misdiagnosis and unnecessary anxiety.

摘要

原理

紫色尿袋综合征(PUBS)是一种罕见但视觉上令人警觉的病症,与尿路感染(UTI)相关,通常发生在长期留置导尿管的体弱老年患者中。认识到PUBS至关重要,因为它可作为潜在感染的一个指标。

患者情况

两名老年男性患者的导尿管袋出现明显的紫色变色。尽管两名患者均否认发热、排尿困难或耻骨上疼痛,但护理人员表示担忧。

诊断

诊断为UTI继发的PUBS。病例1为混合细菌生长,危险因素包括糖尿病、良性前列腺增生、活动不便和长期导尿。病例2为热带念珠菌感染,诱发因素为中风相关的活动不便、便秘和长期导尿。

干预措施

两名患者均接受了Foley导尿管和尿袋更换。病例1接受经验性口服环丙沙星治疗,而病例2需要住院、静脉抗真菌治疗和支持性补液。

结果

更换导尿管后紫色变色消失。两名患者均取得良好效果,无复发。

经验教训

虽然PUBS通常是良性的,但它反映了潜在的UTI,需要及时干预。早期识别、导尿管管理和适当的抗菌治疗是预防并发症的关键。临床医生的认识对于避免误诊和不必要的焦虑至关重要。

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本文引用的文献

1
Purple urine bag syndrome: a unique clinical case and management considerations.紫色尿袋综合征:一个独特的临床病例及处理要点。
BMC Nephrol. 2024 Oct 24;25(1):375. doi: 10.1186/s12882-024-03708-6.
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A Case of Purple Urine Bag Syndrome (PUBS) in a Patient With a Chronic Indwelling Foley Catheter.一例慢性留置导尿管患者的紫色尿袋综合征(PUBS)
Cureus. 2024 Aug 25;16(8):e67731. doi: 10.7759/cureus.67731. eCollection 2024 Aug.
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Purple Urine Bag Syndrome: A Rare Phenomenon Managed in Primary Care.紫色尿袋综合征:基层医疗中处理的一种罕见现象。
Cureus. 2024 Apr 4;16(4):e57620. doi: 10.7759/cureus.57620. eCollection 2024 Apr.
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Purplish Discoloration of Urine in a Patient Receiving Cefiderocol: A Rare Adverse Effect.接受头孢地尔治疗的患者出现尿液紫色变色:一种罕见的不良反应。
J Community Hosp Intern Med Perspect. 2023 Nov 4;13(6):43-46. doi: 10.55729/2000-9666.1256. eCollection 2023.
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A case of purple urinary bag syndrome treated with non-antibiotic methods combined with bladder function training.
Asian J Surg. 2024 May;47(5):2393-2394. doi: 10.1016/j.asjsur.2024.01.055. Epub 2024 Jan 22.
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Purple Urine Bag Syndrome: A Peculiar Presentation of a Urinary Tract Infection.紫色尿袋综合征:尿路感染的一种特殊表现
Cureus. 2023 Dec 1;15(12):e49804. doi: 10.7759/cureus.49804. eCollection 2023 Dec.
7
Prolonged Indwelling Percutaneous Nephrostomy Leading to Purple Urinary Bag Syndrome in Palliative Care Setting: A Case Report.姑息治疗中经皮肾造瘘长期留置导致紫色尿袋综合征:一例报告
Indian J Palliat Care. 2023 Jul-Sep;29(3):324-327. doi: 10.25259/IJPC_162_2022. Epub 2023 Jul 25.
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Purple urine bag syndrome: An unusual manifestation of urinary tract infection, our experience at a tertiary care center.紫色尿袋综合征:尿路感染的一种罕见表现,我们在一家三级医疗中心的经验。
Curr Urol. 2023 Jun;17(2):125-129. doi: 10.1097/CU9.0000000000000044. Epub 2022 Aug 2.
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Purple Urine Bag Syndrome in a Home-Dwelling Elderly Female with Lumbar Compression Fracture: A Case Report.一名患有腰椎压缩性骨折的居家老年女性的紫色尿袋综合征:病例报告
Healthcare (Basel). 2023 Aug 10;11(16):2251. doi: 10.3390/healthcare11162251.
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Purple Urine Bag Syndrome in Urinary Tract Infection.尿路感染中的紫色尿袋综合征
J Glob Infect Dis. 2023 Mar 31;15(2):84-85. doi: 10.4103/jgid.jgid_144_22. eCollection 2023 Apr-Jun.