Tyasningsih Wiwiek, Khairullah Aswin Rafif, Tang John Yew Huat, Effendi Mustofa Helmi, Rehman Saifur, Ma'ruf Ilma Fauziah, Wardhani Bantari Wisynu Kusuma, Moses Ikechukwu Benjamin, Budiastuti Budiastuti, Fauzia Kartika Afrida, Ahmad Riza Zainuddin, Fauziah Ima, Kusala Muhammad Khaliim Jati, Pratama Bima Putra, Kurniasih Dea Anita Ariani, Wibowo Syahputra
Division of Veterinary Microbiology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Open Vet J. 2025 Jun;15(6):2343-2354. doi: 10.5455/OVJ.2025.v15.i6.7. Epub 2025 Jun 30.
Blackleg is an infectious disease that mainly affects cattle and rarely affects other ruminants. It is characterized by hemorrhagic blackleg myositis. is a highly pathogenic anaerobic, endospore-forming Gram- positive bacteria that causes blackleg disease. Blackleg disease was first reported in 1870, but the causative bacterium was not described until 1887. Clostridium chauvoei is found in grassland, fresh water, silage, soil, and the excrement of healthy animals. Cattle intestines and pasture soil have both been found to contain spores, suggesting that the infection is contracted by ingesting the spores. Significant lesions are less common in the heart and more common in the skeletal muscle. Anaerobic culture, polymerase chain reaction, immunodetection using fluorescent antibody tests, and immunohistochemistry are methods for identifying bacteria. The production of gas in animal tissues, known as emphysematous swelling, is a hallmark of blackleg illness. Swelling usually affects big muscles including the neck, shoulders, thighs, and hips. Most incidences of blackleg illness in cattle occur during the warmer months of the year, and the disease typically manifests seasonally. Penicillin treatment and surgical removal of the lesions, including fasciotomy, are recommended for infected animals that are not in danger of death. Vaccination is a crucial part of the health management of many livestock production enterprises and can prevent blackleg illness. Blackleg disease can be controlled by destroying the carcass and burning the top layer of soil to eradicate any remaining spores.
黑腿病是一种主要影响牛、很少影响其他反刍动物的传染病。其特征为出血性黑腿肌炎。产气荚膜梭菌是一种高致病性厌氧、形成芽孢的革兰氏阳性细菌,可引发黑腿病。黑腿病于1870年首次报道,但致病细菌直到1887年才被描述。产气荚膜梭菌存在于草地、淡水、青贮饲料、土壤以及健康动物的粪便中。已发现牛肠道和牧场土壤中均含有该细菌的芽孢,这表明感染是通过摄入芽孢而发生的。明显的病变在心脏中较少见,在骨骼肌中更常见。厌氧培养、聚合酶链反应、使用荧光抗体试验的免疫检测以及免疫组织化学是鉴定细菌的方法。动物组织中产生气体,即气肿肿胀,是黑腿病的一个标志。肿胀通常影响包括颈部、肩部、大腿和臀部在内的大肌肉。牛的黑腿病大多发生在一年中较温暖的月份,且该病通常呈季节性表现。对于没有死亡危险的感染动物,建议进行青霉素治疗并手术切除病变,包括筋膜切开术。疫苗接种是许多畜牧生产企业健康管理的关键部分,可预防黑腿病。可通过销毁尸体和焚烧表层土壤以根除任何残留的芽孢来控制黑腿病。