Santos Janaina Cipriana Dos, Martins Mirian Francisca, Santos-Silva Ludier Kesser
Universidade Federal de Mato Grosso, Programa de Pós-Graduação Stricto Sensu em Imunologia e Parasitologia, Barra do Garças, MT, Brasil.
Escritório Regional de Saúde/Secretaria de Estado de Saúde, Departamento de Vigilância em Saúde Ambiental, Barra do Garças, MT, Brasil.
Rev Soc Bras Med Trop. 2025 Sep 22;58:e01192025. doi: 10.1590/0037-8682-0119-2025. eCollection 2025.
Chagas disease, an anthropozoonosis endemic to Latin America, is caused by Trypanosoma cruzi and is a serious public health concern.
We investigated the natural infection of triatomine bugs, genotyped T. cruzi, and identified the blood meal sources of the infected vectors in the Medio Araguaia region of Mato Grosso, Brazil.
In total, 235 triatomines were identified. The highest triatomine occurrence (95.7%) was observed in the municipality of Barra do Garças. The most prevalent species was Triatoma williami (89.7%), followed by Rhodnius neglectus (8.8%), Panstrongylus geniculatus (0.88%), and Panstrongylus diasi (0.44%). Barra do Garças showed a high rate of natural infection by T. cruzi (65.7%). Four discrete typing units were identified in the infected insects: TcIV and TcII strains in T. williami, and TcI and TcIII associated with R. neglectus and P. geniculatus, respectively. Regarding blood meal sources, T. williami, P. geniculatus, and R. neglectus predominantly fed on birds and rodents. However, human blood was detected in 32.8% of the insects.
Overall, these findings indicate a high risk of Chagas disease vector transmission in the municipality of Barra do Garças, highlighting the need for innovative approaches to control and prevent this disease.
恰加斯病是一种拉丁美洲特有的人畜共患病，由克氏锥虫引起，是一个严重的公共卫生问题。
我们调查了三锥猎蝽的自然感染情况，对克氏锥虫进行基因分型，并确定了巴西马托格罗索州阿腊瓜亚中部地区受感染媒介的血餐来源。
总共鉴定出235只三锥猎蝽。在加尔萨什巴拉市观察到三锥猎蝽的出现率最高（95.7%）。最常见的物种是威廉斯锥猎蝽（89.7%），其次是忽视罗蛉（8.8%）、膝状锥猎蝽（0.88%）和迪亚斯锥猎蝽（0.44%）。加尔萨什巴拉市显示出较高的克氏锥虫自然感染率（65.7%）。在受感染的昆虫中鉴定出四个离散分型单元：威廉斯锥猎蝽中的TcIV和TcII菌株，以及分别与忽视罗蛉和膝状锥猎蝽相关的TcI和TcIII。关于血餐来源，威廉斯锥猎蝽、膝状锥猎蝽和忽视罗蛉主要以鸟类和啮齿动物为食。然而，在32.8%的昆虫中检测到了人类血液。
总体而言，这些发现表明加尔萨什巴拉市存在恰加斯病媒介传播的高风险，突出了需要创新方法来控制和预防这种疾病。
