Hu Xiao, Yu Si-Jie, Gao Yue-Can, Zhao Yan, He Yi-Sheng, Liu Yu-Chen, Pan Hai-Feng, Wang Peng
Department of Health Promotion and Behavioral Sciences, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, China.
Department of Critical Care Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230001, China.
BMC Geriatr. 2025 Sep 24;25(1):693. doi: 10.1186/s12877-025-06344-3.
The global burden of non-communicable diseases (NCDs) among the elderly is rising, yet health inequalities persist across age, sex, and socio-demographic index (SDI) levels.
This study aims to assess global, regional, and national disparities in disease burdens of NCDs among the elderly from 1990 to 2021, with projections up to 2050.
Using data from the Global Burden of Disease Study 2021, we analyzed four key metrics of incidence, prevalence, mortality, and disability-adjusted life years (DALY) for 10 NCDs across age, sex, and SDI levels. Temporal trends were quantified using annual percentage change (AAPC), and projections for NCDs burden up to 2050 were also performed under the assumption of stable socioeconomic conditions.
In 2021, the global age-standardized rates for incidence (ASIR), prevalence (ASPR), mortality (ASMR), and DALY (ASDR) were 182,092.67, 99,905.95, 3,360.06, and 75,380.44 per 100,000 individuals among the elderly population, respectively. From 1990 to 2021, there was a slight increase in the ASPR of NCDs by 0.01%, whereas ASIR, ASMR, and ASDR showed declines with rates of -0.04%, -0.99%, and - 0.77%, respectively. Regions with lower SDI exhibited higher disease burden of NCDs, especially in terms of mortality and disability. Furthermore, the predictions for the NCDs burden among the elderly from 2022 to 2050 indicated an incremental trend in prevalence.
Persistent disparities in the NCDs burdens highlight the need for equitable healthcare strategies. Healthcare providers are encouraged to provide targeted interventions for specific age groups and address differences in healthcare resource allocation among the elderly across different SDI regions.
老年人非传染性疾病(NCDs)的全球负担正在上升,但健康不平等现象在年龄、性别和社会人口指数(SDI)水平上依然存在。
本研究旨在评估1990年至2021年全球、区域和国家层面老年人非传染性疾病疾病负担的差异,并预测至2050年的情况。
利用《2021年全球疾病负担研究》的数据,我们分析了10种非传染性疾病在年龄、性别和SDI水平上的发病率、患病率、死亡率和伤残调整生命年(DALY)这四个关键指标。使用年度百分比变化(AAPC)对时间趋势进行量化,并在社会经济状况稳定的假设下对2050年之前的非传染性疾病负担进行预测。
2021年,老年人口中每10万人的全球年龄标准化发病率(ASIR)、患病率(ASPR)、死亡率(ASMR)和伤残调整生命年率(ASDR)分别为182,092.67、99,905.95、3,360.06和75,380.44。从1990年到2021年,非传染性疾病的年龄标准化患病率略有上升,增幅为0.01%,而年龄标准化发病率、死亡率和伤残调整生命年率分别下降,降幅为-0.04%、-0.99%和-0.77%。SDI较低的地区非传染性疾病负担较高,尤其是在死亡率和伤残方面。此外,2022年至2050年老年人非传染性疾病负担的预测表明患病率呈上升趋势。
非传染性疾病负担的持续差异凸显了公平医疗保健策略的必要性。鼓励医疗保健提供者针对特定年龄组提供有针对性的干预措施,并解决不同SDI地区老年人医疗资源分配的差异。