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哥伦比亚一家眼科转诊中心符合PIVOT试验标准的孔源性视网膜脱离的基线特征:病例系列

Baseline characteristics of rhegmatogenous retinal detachments meeting the PIVOT trial criteria in an eye referral center in Colombia: case series.

作者信息

Salgado-Gómez Danny, Escaf Luis C, Díaz-Granados Gonzalez Omaira, Escobar-DiazGranados Jorge

机构信息

Clínica Oftalmológica del Caribe, Barranquilla, 080020, Colombia.

Department of Ophthalmology, Faculty of Health Sciences, Universidad Simón Bolívar, Barranquilla, Colombia.

出版信息

Int J Retina Vitreous. 2025 Sep 24;11(1):98. doi: 10.1186/s40942-025-00728-8.

Abstract

OBJECTIVE

This study aims to characterize the baseline profile and clinical outcomes of pneumatic retinopexy (PR) in patients fulfilling the Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT) eligibility criteria at a tertiary referral center in Colombia.

METHODS

This retrospective consecutive case series included patients with primary rhegmatogenous retinal detachment (RRD) meeting PIVOT criteria between January 2021 and April 2024. The primary outcome was single-operation success (SOS) at 3 months, defined as complete retinal reattachment after one PR procedure, allowing for a supplementary gas injection within 21 days.

RESULTS

563 newly diagnosed primary RRD cases were reported, 143 (25.4%) were PIVOT-eligible and 105 underwent PR. The SOS rate was 85.7% (90/105). Baseline age, sex, lens status, and macular status were comparable between success and failure groups. Detachment extent > 2 quadrants correlated with an increased risk of failure (p = 0.045); however, this association should be interpreted cautiously given the limited number of events.

CONCLUSIONS

Approximately one-quarter of primary RRD cases at our center met PIVOT criteria. In this cohort, PR yielded a high SOS rate and remains a valuable first-line surgical option in appropriately selected patients, particularly in settings with constrained resources.

摘要

目的

本研究旨在描述在哥伦比亚一家三级转诊中心符合气性视网膜固定术(PR)与玻璃体切除术治疗原发性孔源性视网膜脱离疗效随机试验(PIVOT)纳入标准的患者的基线特征和临床结局。

方法

本回顾性连续病例系列纳入了2021年1月至2024年4月期间符合PIVOT标准的原发性孔源性视网膜脱离(RRD)患者。主要结局是3个月时的单次手术成功(SOS),定义为一次PR手术后视网膜完全复位,允许在21天内进行补充气体注射。

结果

报告了563例新诊断的原发性RRD病例,143例(25.4%)符合PIVOT纳入标准,105例接受了PR治疗。SOS率为85.7%(90/105)。成功组和失败组在基线年龄、性别、晶状体状态和黄斑状态方面具有可比性。脱离范围>2个象限与失败风险增加相关(p = 0.045);然而,鉴于事件数量有限,这种关联应谨慎解释。

结论

我们中心约四分之一的原发性RRD病例符合PIVOT标准。在这个队列中,PR产生了较高的SOS率,并且在适当选择的患者中仍然是一种有价值的一线手术选择,特别是在资源有限的环境中。

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