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多普勒超声能否减少超声引导下经皮肾镜取石术治疗孤立肾结石的出血并发症?

Can Doppler ultrasound reduce hemorrhagic complications in ultrasound-guided percutaneous nephrolithotomy for solitary kidney stones?

作者信息

Xiao Bo, Zeng Xue, Chen Yang, Lin Shen, Xu Yangyang, Huang Haiwen, Luo Zhichao, Bai Wenjie, Li Jianxing

机构信息

Department of Urology, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Beijing, China.

出版信息

Front Surg. 2025 Sep 9;12:1671428. doi: 10.3389/fsurg.2025.1671428. eCollection 2025.

DOI:10.3389/fsurg.2025.1671428
PMID:40994872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12456083/
Abstract

PURPOSE

To evaluate the role of Doppler ultrasound in reducing hemorrhagic events during percutaneous nephrolithotomy (PCNL) in solitary kidney calculi through a comparative analysis.

PATIENTS AND METHODS

We retrospectively reviewed the charts of urolithiasis patients who had undergone ultrasound-guided PCNL in our department from March 2021 to December 2024 and identified 76 eligible patients. Patients were stratified into two cohorts based on Doppler flow detection technology application: Group 1 (Doppler-mode,  = 29) and Group 2 (conventional mode,  = 47). Relevant patient characteristics, operative variables, and postoperative data were collected and analyzed, focusing on bleeding complications and stone-free rate (SFR).

RESULTS

No significant difference was found between the two groups regards to basic characteristics (gender, age, body mass index, stone size, pre-operative serum creatinine). The puncture time shows significant longer in Group 1 compared to Group 2 (173.1 ± 39.6 vs. 111.4 ± 29.9 s,  = 0.02). However, the hemoglobin loss reveals no significant difference between the two groups (17.5 ± 5.6 vs. 21.7 ± 6.3 g/L,  = 0.19). There were no significant differences in the operation duration ( = 0.47), transfusion rate ( = 0.15), postoperative creatinine ( = 0.80), overall complication ( = 0.07), final stone-free rates ( = 0.38) between the two groups.

CONCLUSION

Doppler flow technology fails to confer superior benefits in ultrasound-guided PCNL for solitary renal calculus, with no definitive necessity established for hemorrhage risk mitigation.

摘要

目的

通过对比分析,评估多普勒超声在减少孤立肾结石经皮肾镜取石术(PCNL)期间出血事件中的作用。

患者与方法

我们回顾性分析了2021年3月至2024年12月在我院接受超声引导下PCNL的尿路结石患者的病历,确定了76例符合条件的患者。根据多普勒血流检测技术的应用情况,将患者分为两组:第1组(多普勒模式,n = 29)和第2组(传统模式,n = 47)。收集并分析相关患者特征、手术变量和术后数据,重点关注出血并发症和结石清除率(SFR)。

结果

两组在基本特征(性别、年龄、体重指数、结石大小、术前血清肌酐)方面无显著差异。与第2组相比,第1组的穿刺时间明显更长(173.1±39.6 vs. 111.4±29.9秒,P = 0.02)。然而,两组之间的血红蛋白损失无显著差异(17.5±5.6 vs. 21.7±6.3 g/L,P = 0.19)。两组在手术时长(P = 0.47)、输血率(P = 0.15)、术后肌酐(P = 0.80)、总体并发症(P = 0.07)、最终结石清除率(P = 0.38)方面均无显著差异。

结论

在超声引导下的孤立肾结石PCNL中,多普勒血流技术未能带来更好的益处,在降低出血风险方面没有明确的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f3/12456083/4bee768c93b2/fsurg-12-1671428-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f3/12456083/4bee768c93b2/fsurg-12-1671428-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f3/12456083/4bee768c93b2/fsurg-12-1671428-g001.jpg

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本文引用的文献

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J Ultrasound Med. 2024 Aug;43(8):1543-1562. doi: 10.1002/jum.16466. Epub 2024 Apr 23.
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Contrast-Enhanced Ultrasound for Image-Guided Procedures.对比增强超声在影像引导操作中的应用。
Tech Vasc Interv Radiol. 2023 Sep;26(3):100913. doi: 10.1016/j.tvir.2023.100913. Epub 2023 Oct 20.
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Needle-Perc-Assisted Endoscopic Surgery in Treatment with Renal Staghorn Stones: A Prospective Randomized Controlled Study from a Large-Volume Stone Center.针道辅助内镜手术治疗鹿角状肾结石:一项来自大容量结石中心的前瞻性随机对照研究。
Urol Int. 2023;107(10-12):910-915. doi: 10.1159/000533955. Epub 2023 Oct 26.
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Ultrasound-Only Percutaneous Nephrolithotomy Is Safe and Effective Compared to Fluoroscopy-Directed Percutaneous Nephrolithotomy.与荧光透视引导经皮肾镜取石术相比,仅超声引导经皮肾镜取石术既安全又有效。
J Endourol. 2023 Jun;37(6):634-641. doi: 10.1089/end.2022.0761. Epub 2023 May 9.
5
Is percutaneous nephrolithotomy effective and safe for children with solitary kidney?经皮肾镜取石术治疗孤立肾儿童的有效性和安全性如何?
Pediatr Surg Int. 2022 Aug;38(8):1171-1175. doi: 10.1007/s00383-022-05147-6. Epub 2022 Jun 15.
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Can Color Doppler Ultrasound Challenge the Paradigm in Percutaneous Nephrolithotomy?彩色多普勒超声能否挑战经皮肾镜取石术的范例?
J Endourol. 2022 Mar;36(3):373-380. doi: 10.1089/end.2021.0368. Epub 2022 Mar 1.
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Percutaneous Nephrolithotomy Under X-Ray-Free Technique in Upper Urinary Stone Patients with Autosomal Dominant Polycystic Kidney Disease: Experience from a Large-Volume Stone Management Center.X 射线-Free 技术经皮肾镜取石术治疗常染色体显性多囊肾病上尿路结石患者:大容量结石管理中心的经验。
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Physiology and Pathophysiology of Compensatory Adaptations of a Solitary Functioning Kidney.孤立功能肾代偿性适应的生理学与病理生理学
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