Aljedani Hanan, Mazi Jomanah, Almutairi Arwa, Namnkani Halah, Aldainiy Reffal, Radi Suhaib, Althubaiti Alaa
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Department of Research, King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Int J Endocrinol. 2025 Sep 15;2025:8829049. doi: 10.1155/ije/8829049. eCollection 2025.
Diabetes mellitus (DM) is a growing concern globally. DM control is indicated by hemoglobin A1c, measuring glucose levels within two to 3 months. Patients with DM who have surgery may experience postoperative hyperglycemia (POHG) which is associated with many complications. This study aimed to investigate POHG incidence among patients with DM based on their level of glycemic control. This was a retrospective cohort study of patients with DM ≥ 18 years who had orthopedic, intra-abdominal, cardiothoracic, or vascular surgery at King Abdulaziz Medical City, Jeddah, between October 2016 and October 2023. Patients with DM were considered controlled if the hemoglobin A1c was < 7%. The study included 306 patients, and the majority (69.28%) experienced POHG. There was a significant association between POHG and the level of glycemic control. POHG was experienced by 32.55% of patients with controlled DM vs 67.45% of patients with uncontrolled DM. Furthermore, patients with preoperative random glucose readings (RBG) of ≥ 9.2 mmol/L had a significantly higher risk of developing POHG. Moreover, older age and male sex were associated with higher POHG risk. Our data indicate that the incidence of POHG was significantly greater among patients with uncontrolled DM. Patients with DM with a preoperative RBG of ≥ 9.2 mmol/L had a higher likelihood of developing POHG. Future research should include a larger sample and investigate associations between POHG, other complications, and the influence of varying levels of DM control.
糖尿病（DM）在全球范围内日益受到关注。糖化血红蛋白可用于指示糖尿病的控制情况，它测量的是两到三个月内的血糖水平。接受手术的糖尿病患者可能会经历术后高血糖（POHG），这与许多并发症相关。本研究旨在根据糖尿病患者的血糖控制水平调查术后高血糖的发生率。这是一项回顾性队列研究，研究对象为2016年10月至2023年10月期间在吉达阿卜杜勒阿齐兹国王医疗城接受骨科、腹部、心胸或血管手术的18岁及以上糖尿病患者。如果糖化血红蛋白<7%，则认为糖尿病患者的病情得到了控制。该研究纳入了306名患者，大多数（69.28%）经历了术后高血糖。术后高血糖与血糖控制水平之间存在显著关联。血糖控制良好的糖尿病患者中有32.55%经历了术后高血糖，而血糖控制不佳的患者中这一比例为67.45%。此外，术前随机血糖读数（RBG）≥9.2 mmol/L的患者发生术后高血糖的风险显著更高。此外，年龄较大和男性与术后高血糖风险较高有关。我们的数据表明，血糖控制不佳的糖尿病患者术后高血糖的发生率显著更高。术前RBG≥9.2 mmol/L的糖尿病患者发生术后高血糖的可能性更高。未来的研究应纳入更大的样本，并调查术后高血糖、其他并发症之间的关联以及不同糖尿病控制水平的影响。
