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糖尿病和高血糖作为颌面外科手术术后结局的风险因素。

Diabetes and hyperglycemia as risk factors for postoperative outcome in maxillofacial surgery.

作者信息

Rahimi-Nedjat Roman K, Sagheb Keyvan, Pabst Andreas, Foersch Moritz, Jacobs Collin, Vollandt Leonie, Al-Nawas Bilal, Walter Christian

机构信息

Department of Oral and Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg-University, Mainz, Rheinland-Pfalz, Germany.

Department of Oral and Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg-University, Mainz, Rheinland-Pfalz, Germany.

出版信息

J Surg Res. 2017 Sep;217:170-176. doi: 10.1016/j.jss.2017.05.021. Epub 2017 May 11.

DOI:10.1016/j.jss.2017.05.021
PMID:28602222
Abstract

BACKGROUND

Aim of this study was to investigate the frequency of complications in maxillofacial surgery in-patients in correlation to diabetes mellitus or a pathologically altered glucose metabolism.

MATERIALS AND METHODS

All patients' electronic health records were analyzed retrospectively. Diabetes mellitus anamnesis, the treatment regime, blood glucose levels, and the duration of inpatient treatment were recorded. Glucose readings ≥200 mg/dL measured at any time and fasting glucose levels of ≥110 mg/dL were defined as hyperglycemic. Noted complications were infection, dehiscence, swelling, and necrosis.

RESULTS

8.7% out of 1374 patients had a known diabetes diagnosis. 13.0% had high fasting glucose and 11.4% aberrant maximum glucose readings. Complications did not occur more often in patients with a previously known diabetes but more often in patients with high maximum blood glucose levels. Of these patients, only 56.3% were known diabetics.

CONCLUSIONS

Diabetes mellitus does not necessarily lead to higher frequency of complications in surgical patients. Moreover, patients with well-controlled diabetes seem to have a similar outcome compared to nondiabetics. Hyperglycemia however has an important impact on treatment outcome.

摘要

背景

本研究旨在调查颌面外科住院患者中与糖尿病或病理性糖代谢改变相关的并发症发生频率。

材料与方法

对所有患者的电子健康记录进行回顾性分析。记录糖尿病病史、治疗方案、血糖水平及住院治疗时长。任何时间测得的血糖读数≥200mg/dL以及空腹血糖水平≥110mg/dL被定义为高血糖。记录的并发症包括感染、裂开、肿胀和坏死。

结果

1374例患者中,8.7%有已知糖尿病诊断。13.0%空腹血糖高,11.4%最高血糖读数异常。并发症在既往已知糖尿病患者中并非更常发生,而是在最高血糖水平高的患者中更常发生。在这些患者中,只有56.3%是已知糖尿病患者。

结论

糖尿病不一定导致手术患者并发症发生率更高。此外,血糖控制良好的糖尿病患者与非糖尿病患者的治疗结果似乎相似。然而,高血糖对治疗结果有重要影响。

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