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浪漫伴侣特征与酒精消费及暴饮的关联:检验基因 - 环境相互作用的证据

Associations of Romantic Partners' Characteristics with Alcohol Consumption and Binge Drinking: Examining Evidence for Gene-Environment Interaction.

作者信息

Stephenson Mallory, Cooke Megan E, Barr Peter, Maes Hermine H M, Latvala Antti, Piirtola Maarit, Silventoinen Karri, Rose Richard J, Kaprio Jaakko, Dick Danielle, Salvatore Jessica E

机构信息

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University.

Department of Psychiatry, Robert Wood Johnson Medical School, Rutgers University.

出版信息

Clin Psychol Sci. 2025 Sep;13(5):1006-1028. doi: 10.1177/21677026251332931. Epub 2025 May 5.

DOI:10.1177/21677026251332931
PMID:40995376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12456266/
Abstract

We investigated associations of romantic partners' alcohol use, cigarette smoking, personality, and psychological distress with alcohol use and binge drinking within a sample of Finnish twins who have initiated alcohol use ( = 1620, 51% female, mean age = 33.6 years) and their romantic partners. We also used twin modeling to examine whether partner characteristics moderate genetic influences on drinking behavior. Having a romantic partner with more frequent alcohol use and smoking was consistently associated with greater alcohol consumption and binge drinking, and partner alcohol use and smoking also moderated genetic influences on alcohol consumption. Further, a range of partner characteristics moderated genetic influences on binge drinking, such that the heritability of binge drinking was higher when partners reported less frequent alcohol use, greater smoking, lower conscientiousness, and higher extraversion, neuroticism, and psychological distress. These findings highlight the important, but complex, ways in which romantic partners contribute to drinking behavior.

摘要

我们在一群已开始饮酒的芬兰双胞胎样本(n = 1620,51%为女性,平均年龄 = 33.6岁)及其浪漫伴侣中,研究了浪漫伴侣的饮酒、吸烟、个性和心理困扰与饮酒及暴饮之间的关联。我们还采用双胞胎建模方法,来检验伴侣特征是否会调节基因对饮酒行为的影响。拥有饮酒和吸烟频率更高的浪漫伴侣,始终与更高的酒精消费量和暴饮行为相关联,而且伴侣的饮酒和吸烟行为也会调节基因对酒精消费的影响。此外,一系列伴侣特征会调节基因对暴饮行为的影响,即当伴侣报告饮酒频率较低、吸烟量较大、尽责性较低、外向性、神经质和心理困扰程度较高时,暴饮行为的遗传度更高。这些发现凸显了浪漫伴侣对饮酒行为产生影响的重要但复杂的方式。

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本文引用的文献

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Familial confounding or measurement error? How to interpret findings from sibling and co-twin control studies.家族性混杂还是测量误差?如何解释来自同胞和同卵双生子对照研究的结果。
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