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由金黄色葡萄球菌的磷壁酸导致的对有机粉尘提取物的“假阳性”沉淀反应。技术。

'False positive' precipitation reactions to extracts of organic dusts due to a teichoic acid from S. aureus. Techniques.

作者信息

Faux J A, Holford-Strevens V, Wells I D, Pepys J

出版信息

Clin Exp Immunol. 1970 Dec;7(6):897-902.

Abstract

Precipitation reactions regarded as false positive' have been obtained to extracts of a variety of organic dusts. The antigen responsible for these reactions is an electrophoretically fast moving and negatively charged substance, previously observed in extracts of mouldy hay and other vegetable and organic dusts, and referred to as a D line' antigen. This antigen has now been shown to have antigenic determinants in common with a β-teichoic acid prepared from . Absorption of the sera with -acetyl-D-glucosamine had an inhibitory effect on `D line' and teichoic acid precipitin reactions.

摘要

对多种有机粉尘提取物进行检测时出现了被视为“假阳性”的沉淀反应。引发这些反应的抗原是一种电泳迁移速度快且带负电荷的物质,此前在发霉干草以及其他植物和有机粉尘提取物中观察到过,被称为“D线”抗原。现已证明,该抗原与从……制备的一种β-磷壁酸具有共同的抗原决定簇。用N-乙酰-D-葡萄糖胺吸收血清对“D线”和磷壁酸沉淀素反应具有抑制作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/1712877/6d103e82eb0b/clinexpimmunol00385-0114-a.jpg

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