成人膝关节后交叉韧带损伤的治疗干预措施：一项系统评价与Meta分析方案
Interventions for treating posterior cruciate ligament injuries of the knee in adults: A systematic review and meta-analysis protocol.
作者信息
Sayum Filho Jorge, Tamaoki Marcel Jun Sugawara, Teixeira de Carvalho Rogerio, Nagib Atallah Álvaro, Teruo Matsunaga Fabio, Faloppa Flávio, Carlos Belloti João
机构信息
Department of Orthopaedics and Traumatology, Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil.
Cochrane Brazil, Centro de Estudos de Saúde Baseada em Evidências e Avaliação Tecnológica em Saúde, São Paulo, São Paulo, Brazil.
出版信息
PLoS One. 2025 Sep 25;20(9):e0333015. doi: 10.1371/journal.pone.0333015. eCollection 2025.
INTRODUCTION
There are many different surgical and conservative interventions for treating posterior cruciate ligament (PCL) injuries of the knee in adults. However, in the literature, there is no consensus regarding the best intervention for treating these patients. The objective of this systematic review and meta-analysis is to analyse the effectiveness of interventions (surgical and conservative) for treating PCL injuries of the knee in adults.
METHODS AND ANALYSIS
Starting in November 2025, the authors will accomplish a detailed search using the MEDLINE/PubMed, EMBASE, Cochrane Central Register of Controlled Trials and LILACS databases. Relevant gray literature (academic papers, reference lists theses, technical reports and conference abstracts) will also be included. Two authors will independently screen and extract the information found from randomized controlled trials in the literature. The bias and quality of the included studies will be evaluated using the Risk of Bias 2 tool provided by the Cochrane Collaboration. Statistical analyses will be performed using Review Manager V.5.4/Review Manager Web software.
DISCUSSION
This systematic review is aimed at providing practical information for Orthopaedic surgeons on the effectiveness of the interventions (surgical and conservative) for treating PCL injuries of the knee in adults.
PROSPERO REGISTRATION NUMBER
CRD42023430493.
引言
对于治疗成人膝关节后交叉韧带（PCL）损伤，有许多不同的手术和保守干预措施。然而，在文献中，对于治疗这些患者的最佳干预措施尚无共识。本系统评价和荟萃分析的目的是分析治疗成人膝关节PCL损伤的干预措施（手术和保守）的有效性。
方法与分析
从2025年11月开始，作者将使用MEDLINE/PubMed、EMBASE、Cochrane对照试验中央注册库和LILACS数据库进行详细检索。相关灰色文献（学术论文、参考文献列表、论文、技术报告和会议摘要）也将被纳入。两名作者将独立筛选并提取文献中随机对照试验的信息。纳入研究的偏倚和质量将使用Cochrane协作网提供的偏倚风险2工具进行评估。将使用Review Manager V.5.4/Review Manager Web软件进行统计分析。
讨论
本系统评价旨在为骨科医生提供关于治疗成人膝关节PCL损伤的干预措施（手术和保守）有效性的实用信息。
PROSPERO注册号：CRD42023430493。
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