Iurovitskiĭ Iu G, Krivopishin I P, Mil'man L S
Ontogenez. 1977;8(5):527-31.
In the chick embryo liver the portion of granular glycogen increases from 15 to 90% of the total content during the period from the 8th till the 14th days of developments. The activity of glycogen synthetase (KF 2.4.1.11) localized in the fraction of granular glycogen increases from 40 to 90% of the total activity in the 18 days old embryo. The activity of phosphorylase (KF 2.4.1.1) is detected in the granular glycogen of the liver only on the 12th day of development (10% of the total activity) and increase up to 80% on the 19th day of development. The maximal activation of glycogen synthetase and phosphorylase is noted after the glycosomes of formation in the developing embryoliver. A suggestion is put forward to the effect that the process of glycosome formation is a factor of the control of glycogen synthetase and phosphorylase activity.
在鸡胚肝脏中,从发育的第8天到第14天,颗粒状糖原的比例从总含量的15%增加到90%。定位于颗粒状糖原部分的糖原合成酶(KF 2.4.1.11)的活性在18日龄胚胎中从总活性的40%增加到90%。磷酸化酶(KF 2.4.1.1)的活性仅在发育的第12天在肝脏的颗粒状糖原中检测到(占总活性的10%),并在发育的第19天增加到80%。在发育中的胚胎肝脏中糖体形成后,糖原合成酶和磷酸化酶出现最大程度的激活。有人提出,糖体形成过程是控制糖原合成酶和磷酸化酶活性的一个因素。