Chen Pengyu, Al-Hadad Saba Ahmed, Rao Chenyu, Li Yi, Li Chunshen, ALyafrusee Enas Senan, Al-Tayar Barakat, Almagrami Ibtehal, Al-Warafi Leena Ali, Chen Xi, Zhao Yunshan
Department of Stomatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xian, 710061, Shaanxi, People's Republic of China.
Department of Orthodontics and Dentofacial Orthopedics, Faculty of Dentistry, Ibb University, Ibb, Republic of Yemen.
Sci Rep. 2025 Sep 25;15(1):32874. doi: 10.1038/s41598-025-17583-0.
Stabilization splint (SS) therapy is commonly used to treat temporomandibular disorders (TMD), but its three-dimensional (3D) effects on pharyngeal airway (PA) dimensions, hyoid bone (HB) position, and craniocervical (CC) posture remain unclear. This study primarily aimed to evaluate the 3D changes in the PA, with a secondary focus on the HB and CC posture, in adult TMD patients after SS therapy. This retrospective study analyzed 80 adult TMD patients (mean age: 23.88 ± 5.8 years) treated with SS for 6-12 months. Pre- and post-treatment cone-beam computed tomography (CBCT) scans were used to measure 3D changes in PA (naso-, oro-, hypo-, and total pharyngeal spaces), HB position, and CC posture using InVivo and Dolphin software. Statistical analysis included paired t-tests and Wilcoxon signed-rank test (P < 0.05). Significant reductions occurred in oropharyngeal surface area and sagittal width (P = 0.021; P = 0.017, respectively) and hypopharyngeal parameters (surface area, volume, minimal constriction area, sagittal width; P < 0.05). HB measurements showed significant decrease in hyoid-mandibular plane (H-MP), hyoid-retrognathia distances (H-RGN) and hyoid triangle height measurements (P = 0.002, P = 0.014 and P = 0.029, respectively), with a significant increase in retrognathia-sella distance (RGN-S, P = 0.003). CC posture showed significant decreases in the Sella-Nasion to odontoid process tangent angle (SNL-OPT) and to the cervical vertebra tangent angle (SNL-CVT) (P = 0.005, P = 0.003, respectively). SS therapy significantly reduced oropharyngeal and hypopharyngeal airway dimensions, changed HB position, and improved CC posture post-treatment. These results highlight the multidimensional impact of SS therapy and support incorporating airway and CC posture assessments into TMD management which enhances diagnosis and therapeutic outcomes.
稳定型矫治器(SS)疗法常用于治疗颞下颌关节紊乱病(TMD),但其对咽气道(PA)尺寸、舌骨(HB)位置和颅颈(CC)姿势的三维(3D)影响尚不清楚。本研究主要旨在评估成年TMD患者接受SS治疗后PA的三维变化,其次关注HB和CC姿势。这项回顾性研究分析了80例接受SS治疗6至12个月的成年TMD患者(平均年龄:23.88±5.8岁)。使用治疗前和治疗后的锥形束计算机断层扫描(CBCT)扫描,通过InVivo和Dolphin软件测量PA(鼻、口、下咽和总咽间隙)的三维变化、HB位置和CC姿势。统计分析包括配对t检验和Wilcoxon符号秩检验(P<0.05)。口咽表面积和矢状宽度(分别为P = 0.021;P = 0.017)以及下咽参数(表面积、体积、最小收缩面积、矢状宽度;P<0.05)出现显著减小。HB测量显示舌骨-下颌平面(H-MP)、舌骨-下颌后缩距离(H-RGN)和舌骨三角高度测量值显著降低(分别为P = 0.002、P = 0.014和P = 0.029),而下颌后缩-蝶鞍距离(RGN-S,P = 0.003)显著增加。CC姿势显示蝶鞍-鼻根至齿突切线角(SNL-OPT)和至颈椎切线角(SNL-CVT)显著减小(分别为P = 0.005、P = 0.003)。SS治疗显著减小了口咽和下咽气道尺寸,改变了HB位置,并改善了治疗后的CC姿势。这些结果突出了SS治疗的多维度影响,并支持将气道和CC姿势评估纳入TMD管理,这有助于提高诊断和治疗效果。