An Delin, Du Pan, Gu Pengfei, Wang Jian-Xun, Wang Chaoli
Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN.
Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN.
Proc IEEE Int Symp Biomed Imaging. 2025 Apr;2025. doi: 10.1109/isbi60581.2025.10980947. Epub 2025 May 12.
Accurate segmentation of the aorta and its associated arch branches is crucial for diagnosing aortic diseases. While deep learning techniques have significantly improved aorta segmentation, they remain challenging due to the intricate multiscale structure and the complexity of the surrounding tissues. This paper presents a novel approach for enhancing aorta segmentation using a Bayesian neural network-based hierarchical Laplacian of Gaussian (LoG) model. Our model consists of a 3D U-Net stream and a hierarchical LoG stream: the former provides an initial aorta segmentation, and the latter enhances blood vessel detection across varying scales by learning suitable LoG kernels, enabling self-adaptive handling of different parts of the aorta vessels with significant scale differences. We employ a Bayesian method to parameterize the LoG stream and provide confidence intervals for the segmentation results, ensuring robustness and reliability of the prediction for vascular medical image analysts. Experimental results show that our model can accurately segment main and supra-aortic vessels, yielding at least a 3% gain in the Dice coefficient over state-of-the-art methods across multiple volumes drawn from two aorta datasets, and can provide reliable confidence intervals for different parts of the aorta. The code is available at https://github.com/adlsn/LoGBNet.
准确分割主动脉及其相关的弓状分支对于诊断主动脉疾病至关重要。虽然深度学习技术显著改善了主动脉分割,但由于复杂的多尺度结构和周围组织的复杂性,它们仍然具有挑战性。本文提出了一种基于贝叶斯神经网络的高斯分层拉普拉斯(LoG)模型来增强主动脉分割的新方法。我们的模型由一个3D U-Net流和一个分层LoG流组成:前者提供主动脉的初始分割,后者通过学习合适的LoG核增强不同尺度下的血管检测,能够自适应处理具有显著尺度差异的主动脉血管不同部分。我们采用贝叶斯方法对LoG流进行参数化,并为分割结果提供置信区间,确保为血管医学图像分析人员提供稳健且可靠的预测。实验结果表明,我们的模型能够准确分割主动脉主干和主动脉弓血管,在从两个主动脉数据集中抽取的多个体积上,与现有方法相比,Dice系数至少提高了3%,并且能够为主动脉的不同部分提供可靠的置信区间。代码可在https://github.com/adlsn/LoGBNet获取。