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口服营养补充剂对改善腹泻儿童状况的影响:一项系统评价

The Effect of Oral Nutritional Supplements in Improving the Condition of Children with Diarrhea: A Systematic Review.

作者信息

Mahmoudifar Kamiar, Hashempoor Mehrara, Asadi Touranlou Fateme, Rezaie Mitra

机构信息

Department of Nutrition, Mashhad University of Medical Sciences Faculty of Medicine, Mashhad, Iran.

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2025 Sep;28(5):267-279. doi: 10.5223/pghn.2025.28.5.267. Epub 2025 Sep 9.

DOI:10.5223/pghn.2025.28.5.267
PMID:41001439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12457807/
Abstract

Despite advances in the understanding of disease pathogenesis and treatment, diarrhea remains the primary cause of death among children around the world. Nutrition plays a significant role in treating diarrheal diseases. Malnourished children who have infectious diarrhea are at great risk of developing prolonged and more severe symptoms. The objective of this study was to review the effects of oral nutritional supplements on children with diarrhea. A systematic search for information was conducted using specific keywords in several databases. The results showed that oral food supplements are effective in reducing the symptoms of diarrhea, and the success rate with some formulations reached 100%. The rate of success and failure of formulas of oral nutritional supplements is dependent on the ingredients and foods used: Supplements high in zinc and fiber, as well as the foods yogurt and lactose-free milk, had the greatest impact on the success rate. Oral nutritional supplements are an effective way to reduce the duration and symptoms of diarrhea and can be used to treat diarrhea.

摘要

尽管在疾病发病机制和治疗的理解方面取得了进展,但腹泻仍然是全球儿童死亡的主要原因。营养在治疗腹泻疾病中起着重要作用。患有感染性腹泻的营养不良儿童极易出现长期且更严重的症状。本研究的目的是回顾口服营养补充剂对腹泻儿童的影响。使用特定关键词在多个数据库中进行了系统的信息检索。结果表明,口服食物补充剂在减轻腹泻症状方面是有效的,一些配方的成功率达到了100%。口服营养补充剂配方的成功率和失败率取决于所使用的成分和食物:富含锌和纤维的补充剂,以及酸奶和无乳糖牛奶等食物,对成功率的影响最大。口服营养补充剂是缩短腹泻持续时间和减轻腹泻症状的有效方法,可用于治疗腹泻。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe4/12457807/3c6471acdf36/pghn-28-267-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe4/12457807/3c6471acdf36/pghn-28-267-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe4/12457807/3c6471acdf36/pghn-28-267-g001.jpg

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The recent WHO guideline on acute malnutrition overestimates therapeutic energy requirement.世界卫生组织最近关于急性营养不良的指南高估了治疗能量需求。
Lancet Reg Health Southeast Asia. 2024 May 21;25:100419. doi: 10.1016/j.lansea.2024.100419. eCollection 2024 Jun.
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The Role of Short Chain Fatty Acids in Irritable Bowel Syndrome.短链脂肪酸在肠易激综合征中的作用
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Nutrients. 2021 May 31;13(6):1896. doi: 10.3390/nu13061896.
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Dig Dis. 2021;39(6):615-621. doi: 10.1159/000515219. Epub 2021 Feb 15.
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Effects of oral nutrition supplements in persons with dementia: A systematic review.痴呆患者口服营养补充剂的效果:系统评价。
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