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肝硬化的营养管理:一项系统性综述与观察性研究的联合分析

Nutritional Management in Liver Cirrhosis: A Combined Systematic Review and Observational Study.

作者信息

Amariței Valentina, Gheorghita Roxana-Elena, Caliman Sturdza Olga Adriana

机构信息

College of Medicine and Biological Sciences, Department of Biological and Morphofunctional Sciences, Stefan cel Mare University of Suceava, 720229 Suceava, Romania.

College of Medicine and Biological Sciences, Department of Medical-Surgical and Complementary Sciences, Stefan cel Mare University of Suceava, 720229 Suceava, Romania.

出版信息

Diseases. 2025 Aug 25;13(9):278. doi: 10.3390/diseases13090278.

Abstract

BACKGROUND

Liver cirrhosis is a complex and chronic pathology with the potential to impact a number of factors, including the patient's health, nutritional status and diet. Proper nutritional intake plays an essential role alongside the necessary medical and recovery treatments.

METHODS

This study was conducted on a group that included patients of varying age demographics. They were required to undertake a 24 h food recall as well as two other questionnaires (CNAQ and CLDQ-NASH) that reported the level of appetite and nutrition and other aspects that focused on the patient's general health and quality of life, respectively.

RESULTS

The results of the study indicated the presence of reduced appetite and a decrease in quality of life, as reported by questionnaire scores of less than 28 points for appetite and less than 4 points for quality of life. The 24 h dietary recalls revealed that the majority of patients exhibited a preference for meals comprising red and processed meats and traditional foods such as soups and animal foods and a low consumption of white meat, fish, legumes and fiber.

CONCLUSIONS

The study's findings reveal an imbalance in the patients' nutritional intake and underscore the critical importance of nutritional support for patients with liver cirrhosis. However, further research is needed in this regard to determine the factors leading to nutritional deficiencies and the causes leading to refusal of nutritional intervention within the management of this disease.

摘要

背景

肝硬化是一种复杂的慢性病理状态,有可能影响诸多因素,包括患者的健康、营养状况和饮食。在必要的医学及康复治疗的同时,适当的营养摄入起着至关重要的作用。

方法

本研究针对一个包含不同年龄人群的患者组开展。他们被要求进行24小时食物回顾调查,以及另外两份问卷(CNAQ和CLDQ-NASH),这两份问卷分别报告了食欲和营养水平以及关注患者总体健康和生活质量的其他方面。

结果

研究结果表明,食欲下降和生活质量降低,食欲问卷得分低于28分,生活质量问卷得分低于4分。24小时饮食回顾显示,大多数患者偏爱包含红肉和加工肉类以及汤类和动物性食物等传统食物的膳食,而白肉、鱼类、豆类和纤维的摄入量较低。

结论

该研究结果揭示了患者营养摄入的不均衡,并强调了营养支持对肝硬化患者的至关重要性。然而,在这方面需要进一步研究,以确定导致营养缺乏的因素以及在该疾病管理中导致拒绝营养干预的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ce5/12468646/01f693c21143/diseases-13-00278-g001.jpg

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