Nappi Francesco
Department of Cardiac Surgery, Centre Cardiologique du Nord, 93200 Saint-Denis, France.
Biomimetics (Basel). 2025 Sep 4;10(9):590. doi: 10.3390/biomimetics10090590.
Suture materials are of pivotal importance in the process of wound healing, as they provide support to growing tissue. The application of suture materials is an intricate process that extends beyond mere closure of skin wounds. Rather, it encompasses a wide range of surgical procedures. It is evident that suture materials possess a high degree of versatility, as evidenced by their application in a broad range of surgical disciplines, including, but not limited to, plastic surgery, neurosurgery, vascular surgery and ocular surgery. Additionally, their application extends to wound treatment and the repair of the musculo-skeletal system and the urogenital tract. This review underscores the pivotal role of sutures in contemporary medicine and surgery. The selection of suture material must be made with the utmost attention to the physical and biological characteristics of the material concerned. The process is characterised by a multifaceted evaluation encompassing the following: first, the assessment of the wound in question; secondly, the healing rate of different tissue types; and thirdly, a thorough appraisal of the patient's overall physical condition. Advances in suture material technology have given rise to a wider range of sutures, thereby enhancing the existing array of options. Simultaneously, suture needles have undergone a progressive process of technological refinement, resulting in a more comprehensive range of alternatives with a heightened level of precision for specific applications in tissue engineering. Recent experimental investigations have employed an animal model, underpinned by biomechanical analysis. It is evident from the findings of these studies that absorbable sutures fulfil a scaffolding function. The hypothesis concerning the biomimetic function of the materials under investigation was corroborated by the results of biomechanical behaviour and histological examination. This review explores the functionality of both absorbable sutures and novel polymers, investigating their potential application as scaffolding materials within clinical contexts.
缝合材料在伤口愈合过程中至关重要，因为它们为生长中的组织提供支撑。缝合材料的应用是一个复杂的过程，不仅仅是简单地闭合皮肤伤口。相反，它涵盖了广泛的外科手术。显然，缝合材料具有高度的通用性，这从它们在广泛的外科领域中的应用得到证明，包括但不限于整形外科、神经外科、血管外科和眼科手术。此外，它们的应用还扩展到伤口治疗以及肌肉骨骼系统和泌尿生殖道的修复。本综述强调了缝线在当代医学和外科中的关键作用。缝合材料的选择必须极其关注相关材料的物理和生物学特性。这个过程的特点是多方面的评估，包括：第一，对所讨论伤口的评估；第二，不同组织类型的愈合速度；第三，对患者整体身体状况的全面评估。缝合材料技术的进步带来了更多种类的缝线，从而增加了现有的选择范围。同时，缝合针也经历了逐步的技术改进，产生了更全面的替代品，在组织工程的特定应用中具有更高的精度。最近的实验研究采用了动物模型，并辅以生物力学分析。从这些研究的结果可以明显看出，可吸收缝线起到了支架作用。关于所研究材料的仿生功能的假设得到了生物力学行为和组织学检查结果的证实。本综述探讨了可吸收缝线和新型聚合物的功能，研究它们作为临床环境中支架材料的潜在应用。
