Zickus Julia R, Enriquez José S, Smith Paytience, Sun Bill T, Wang Muxin, Morales Aldo, Bhattacharya Pratip K, Pudakalakatti Shivanand
Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Graduate School of Biomedical Sciences, University of Texas MD Anderson Cancer Center UT Health Houston, Houston, TX 77030, USA.
Metabolites. 2025 Sep 11;15(9):607. doi: 10.3390/metabo15090607.
Nuclear magnetic resonance (NMR) spectroscopy is a routinely used analytical tool for studying chemical entities of varying molecular sizes, ranging from approximately 20 Da to ~45 kDa, and in some cases even larger. Over the past two decades, the use of NMR spectroscopy has significantly expanded to the study of metabolomics. In this medium-sized review, the application of NMR-based metabolomics in the diagnosis, therapeutic intervention, and guidance of therapy for various types of brain cancer is discussed.
核磁共振（NMR）光谱法是一种常用的分析工具，用于研究分子大小各异的化学实体，范围从大约20道尔顿到~45千道尔顿，在某些情况下甚至更大。在过去二十年中，NMR光谱法的应用已显著扩展到代谢组学研究。在这篇中型综述中，讨论了基于NMR的代谢组学在各类脑癌的诊断、治疗干预和治疗指导中的应用。
