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Early epidural analgesia for the preoperative management of suspected spontaneous pheochromocytoma rupture: a case report.

作者信息

Oshiba Yukina, Shibata Sho C, Lee Taehun, Inoue Junichi, Kita Takashi

机构信息

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Department of Anesthesiology, Osaka International Medical & Science Center, Osaka, Japan.

出版信息

JA Clin Rep. 2025 Sep 26;11(1):49. doi: 10.1186/s40981-025-00813-9.

Abstract

BACKGROUND

Acute abdominal pain is an uncommon manifestation of pheochromocytoma. Poor pain management may delay preoperative optimization of hemodynamics and intravascular blood volume. We report a case in which early epidural analgesia facilitated preoperative preparation for a laparoscopic adrenalectomy.

CASE PRESENTATION

A female patient diagnosed with pheochromocytoma developed the sudden onset of severe left lower abdominal pain, hypertension, nausea, and vomiting. Pain treatment with acetaminophen and loxoprofen was insufficient, and opioids were avoided due to persistent nausea and constipation. Initiation of continuous thoracic epidural analgesia with 0.25% levobupivacaine resulted in rapid pain relief and improved gastrointestinal symptoms. Over a 9-day period, blood pressure and intravascular blood volume were optimized while epidural analgesia was continued. She underwent a successful adrenalectomy and was discharged without complications.

CONCLUSIONS

This case illustrates the potential utility of early epidural analgesia in the preoperative management of pheochromocytoma, particularly in patients with refractory abdominal pain and limited opioid tolerance.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c9/12474838/5b578cf65eca/40981_2025_813_Fig1_HTML.jpg

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