Lampropoulos Ioannis Ch, Malli Foteini, Aggelopoulos Eleftherios, Tsameti Angeliki, Rouka Erasmia, Daniil Zoe, Gourgoulianis Konstantinos I
Respiratory Medicine Department, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Department of Nursing, University of Thessaly, 41500 Larissa, Greece.
Healthcare (Basel). 2025 Sep 13;13(18):2293. doi: 10.3390/healthcare13182293.
The objective of the present study was to systematically explore the scientific literature to examine the relationship between respiratory diseases and economic cost. The research question focused on identifying the thematic, methodological, and temporal trends that link these two scientific fields. A comprehensive search was conducted in the PubMed database using the terms "Pulmonology OR respiratory" AND "Cost", which returned 30,274 publications from 1921 up to April 2025. For the bibliometric review, VOSviewer software was used to create bibliometric maps through the tools of network, overlay, and density visualization. The analysis revealed six clusters, which include clinical prognosis, pandemics, pharmacoeconomics, epidemiology, chronic conditions, and health services research. After 2010, there was a particularly important increase in academic research related to pulmonology and cost, with this rise being especially evident during and after the COVID-19 pandemic. Recent studies have increasingly focused on cost-effectiveness, quality of life, hospitalization, and multimorbidity. The scientific field of respiratory conditions is undergoing a substantial transformation, shifting from traditional clinical descriptions to an interdisciplinary framework that incorporates economic evaluation. This evolution highlights the need for strategies based on economically informed decisions and effective public health policy making. The term "economic cost" in this study refers to both direct costs (e.g., hospitalization and treatment) and indirect economic impacts, such as resource allocation and healthcare burden. The findings demonstrate that research linking respiratory diseases and economic cost is expanding rapidly, particularly after the COVID-19 pandemic, and is characterized by interdisciplinary approaches that combine clinical, epidemiological, and economic perspectives. This trend underlines the importance of integrating cost-effectiveness considerations into respiratory healthcare policies and highlights the need for collaborative strategies to ensure sustainable and efficient health systems.
本研究的目的是系统地探索科学文献，以检验呼吸系统疾病与经济成本之间的关系。研究问题聚焦于确定连接这两个科学领域的主题、方法和时间趋势。在PubMed数据库中使用术语“肺病学或呼吸”和“成本”进行了全面搜索，检索出了从1921年到2025年4月的30274篇出版物。对于文献计量学综述，使用VOSviewer软件通过网络、叠加和密度可视化工具创建文献计量图。分析揭示了六个聚类，包括临床预后、大流行、药物经济学、流行病学、慢性病和卫生服务研究。2010年之后，与肺病学和成本相关的学术研究有了特别显著的增加，这种增长在新冠疫情期间及之后尤为明显。最近的研究越来越关注成本效益、生活质量、住院治疗和多病共存。呼吸系统疾病的科学领域正在经历重大变革，从传统的临床描述转向纳入经济评估的跨学科框架。这一演变凸显了基于经济明智决策和有效公共卫生政策制定的策略的必要性。本研究中的“经济成本”一词既指直接成本（如住院和治疗），也指间接经济影响，如资源分配和医疗负担。研究结果表明，将呼吸系统疾病与经济成本联系起来的研究正在迅速扩展，尤其是在新冠疫情之后，其特点是结合了临床、流行病学和经济视角的跨学科方法。这一趋势强调了将成本效益考虑纳入呼吸保健政策的重要性，并凸显了采取协作策略以确保卫生系统可持续和高效的必要性。
