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如何进行心脏对比增强超声检查(cCEUS):第二部分——高级应用与解读

How to Perform Cardiac Contrast-Enhanced Ultrasound (cCEUS): Part II-Advanced Applications and Interpretation.

作者信息

Becher Harald, Helfen Andreas, Michels Guido, Gaibazzi Nicola, Senior Roxy, Dietrich Christoph Frank

机构信息

Mazankowski Alberta Heart Institute, Edmonton, AB T6G 2B7, Canada.

St. Marien Hospital, 44534 Lünen, Germany.

出版信息

Diagnostics (Basel). 2025 Sep 18;15(18):2371. doi: 10.3390/diagnostics15182371.

DOI:10.3390/diagnostics15182371
PMID:41008743
Abstract

Ultrasound enhancing agents (UEAs, formerly called contrast agents) have enhanced echocardiographic diagnostics of myocardial disease and masses as well as myocardial perfusion abnormalities. This review provides up-to-date guidance on the procedures and interpretations according to current recommendations of imaging societies and considering the results of recent major studies. For the different indications, a standardized approach has been created including technical aspects, pre-assessment and primary scan planes, contrast-enhanced ultrasound (CEUS) procedure, interpretation and reporting. In a previous publication (part 1) the UEAs, imaging methods, preparation of the patients and assessment of global and regional LV function with UEAs were included. The two parts represent a comprehensive state-of-the-art compendium on how to perform CEUS examinations in clinical echocardiography and provide advice on education, qualification and quality control.

摘要

超声增强剂(UEAs,以前称为造影剂)已改善了对心肌病、肿块以及心肌灌注异常的超声心动图诊断。本综述根据影像学会的当前建议并考虑近期主要研究结果,提供了有关程序和解读的最新指南。针对不同适应证,已制定了标准化方法,包括技术方面、预评估和主要扫描平面、对比增强超声(CEUS)程序、解读和报告。在之前的一篇出版物(第1部分)中,介绍了超声增强剂、成像方法、患者准备以及使用超声增强剂评估左心室整体和局部功能。这两部分代表了一份关于如何在临床超声心动图中进行对比增强超声检查的全面的最新纲要,并就教育、资质和质量控制提供了建议。

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本文引用的文献

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How to Perform Cardiac Contrast-Enhanced Ultrasound (cCEUS): Part I.如何进行心脏对比增强超声检查(cCEUS):第一部分。
Diagnostics (Basel). 2025 Jul 9;15(14):1743. doi: 10.3390/diagnostics15141743.
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Multi-societal expert consensus statement on the safe administration of ultrasound contrast agents.关于超声造影剂安全使用的多学会专家共识声明。
Echo Res Pract. 2025 Feb 21;12(1):4. doi: 10.1186/s44156-024-00068-7.
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The clinical use of stress echocardiography in chronic coronary syndromes and beyond coronary artery disease: a clinical consensus statement from the European Association of Cardiovascular Imaging of the ESC.
超声心动图负荷试验在慢性冠状动脉综合征及冠状动脉疾病以外的临床应用:来自欧洲心血管影像协会 ESC 的临床共识声明。
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Safety of Lumason® (SonoVue®) in special populations and critically ill patients.Lumason®(声诺维®)在特殊人群和重症患者中的安全性。
Front Cardiovasc Med. 2023 Aug 2;10:1225654. doi: 10.3389/fcvm.2023.1225654. eCollection 2023.
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Excessive Trabeculation of the Left Ventricle: JACC: Cardiovascular Imaging Expert Panel Paper.左心室小梁过度增生:JACC:心血管成像专家小组论文。
JACC Cardiovasc Imaging. 2023 Mar;16(3):408-425. doi: 10.1016/j.jcmg.2022.12.026. Epub 2023 Feb 8.
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Management of Patients at Risk for and With Left Ventricular Thrombus: A Scientific Statement From the American Heart Association.左心室血栓风险患者及左心室血栓患者的管理:美国心脏协会科学声明
Circulation. 2022 Oct 11;146(15):e205-e223. doi: 10.1161/CIR.0000000000001092. Epub 2022 Sep 15.
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How to perform an ultrasound contrast myocardial perfusion examination?如何进行超声造影心肌灌注检查?
Eur Heart J Cardiovasc Imaging. 2022 Jun 1;23(6):727-729. doi: 10.1093/ehjci/jeac028.
8
Echocardiographic features of left ventricular recess, cleft, diverticulum, and aneurysm: A systematic review.左心室憩室、裂孔、憩室和瘤的超声心动图特征:系统评价。
J Clin Ultrasound. 2022 Mar;50(3):339-346. doi: 10.1002/jcu.23155. Epub 2022 Feb 11.
9
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Med Klin Intensivmed Notfmed. 2022 Feb;117(Suppl 1):1-23. doi: 10.1007/s00063-021-00891-4.
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J Am Soc Echocardiogr. 2021 Dec;34(12):1262-1272. doi: 10.1016/j.echo.2021.07.015. Epub 2021 Aug 8.