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视黄醇和视黄酸对维生素A缺乏大鼠睾丸磷脂酶a活性的影响。

The effect of retinol and retinoic acid on the testicular phospholipase a activity in retinol-deficient rats.

作者信息

Chaudhary L R

出版信息

Biochim Biophys Acta. 1976 Mar 26;424(3):489-92. doi: 10.1016/0005-2760(76)90041-2.

Abstract

Both phospholipases A1 and A2 activities (EC 3.1.1.4) at pH 7.4 were found to be significantly decreased in retinol-deficient rat testes supplemented with retinoic acid as compared to retinol-fed controls using 1-acyl-2-[1-(14)C]-oleoyl-sn-glycero-3-phosphocholine as substrate. However, little or no difference was observed in phospholipase A1 activity at pH 3.0 in both groups of rats.

摘要

与喂食视黄醇的对照组相比,以1-酰基-2-[1-(14)C]-油酰基-sn-甘油-3-磷酸胆碱为底物,发现在补充视黄酸的维生素A缺乏大鼠睾丸中,pH 7.4时磷脂酶A1和A2的活性(EC 3.1.1.4)均显著降低。然而,两组大鼠在pH 3.0时磷脂酶A1的活性几乎没有差异。

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