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筛查人群中犬内侧冠状突疾病的跨模态诊断一致性:424个肘关节的X光片与CT对比

Cross-Modality Diagnostic Agreement in Canine Medial Coronoid Disease in a Screening Population: Radiographs vs. CT in 424 Elbow Joints.

作者信息

Vali Yasamin, Villamonte Chevalier Aquilino, van Bree Henri, Broeckx Bart J G, Gielen Ingrid

机构信息

Diagnostic Imaging, Department of Small Animals and Horses, University of Veterinary Medicine, 1210 Vienna, Austria.

Department of Morphology, Imaging, Orthopedics, Rehabilitation and Nutrition, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium.

出版信息

Vet Sci. 2025 Sep 12;12(9):883. doi: 10.3390/vetsci12090883.

Abstract

Diagnostic imaging is a crucial non-invasive tool for evaluating canine elbow joints, particularly for screening and treatment planning of medial coronoid disease (MCD). Radiography remains the most accessible and widely used screening modality, but its diagnostic accuracy varies significantly. Sensitivity values reported in previous studies vary depending on factors such as study population, imaging technique, and interpretation criteria. This study compared four measures (sensitivity, specificity, positive and negative predictive value) of radiography with a more advanced imaging method, computed tomography (CT), which provides more detailed images of bones. The results showed that radiography correctly identified 65% of the cases (17/26), while missing some of the affected joints. Furthermore, 7% of the healthy joints (29/398) were misdiagnosed as diseased, leading to a specificity of 93% (369/398). For a disease prevalence of 6% (26/424), the positive and negative predictive value of radiography were 37% (17/46) and 98% (369/378), respectively. Overall, when CT is available, it is the preferred technique for screening. In cases where it is not available, it is important to have an idea of the sensitivity and specificity, but also of the positive and negative predictive value, especially at low prevalences. These results help veterinarians make better decisions when screening for elbow problems in dogs.

摘要

诊断成像对于评估犬肘关节是一种至关重要的非侵入性工具,特别是在内侧冠状突疾病(MCD)的筛查和治疗规划方面。X线摄影仍然是最容易获得且广泛使用的筛查方式,但其诊断准确性差异很大。先前研究报告的敏感度值因研究人群、成像技术和解读标准等因素而有所不同。本研究将X线摄影的四项指标(敏感度、特异度、阳性预测值和阴性预测值)与一种更先进的成像方法——计算机断层扫描(CT)进行了比较,CT能提供更详细的骨骼图像。结果显示,X线摄影正确识别了65%的病例(17/26),但遗漏了一些受影响的关节。此外,7%的健康关节(29/398)被误诊为患病,特异度为93%(369/398)。对于6%(26/424)的疾病患病率,X线摄影的阳性预测值和阴性预测值分别为37%(17/46)和98%(369/378)。总体而言,若有CT可用,它是筛查的首选技术。在没有CT的情况下,了解敏感度、特异度以及阳性和阴性预测值很重要,尤其是在患病率较低时。这些结果有助于兽医在筛查犬肘关节问题时做出更好的决策。

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