Gurijala Samhitha, Malik Sofia, Ganti Latha
Prosper HS, Prosper, TX, USA.
Washington University in St. Louis, St. Louis, MO, USA.
Int J Emerg Med. 2025 Sep 26;18(1):171. doi: 10.1186/s12245-025-01007-x.
A bibliometric analysis was performed on academic research from 1965 to 2025 with a focus on S-100B protein and acute ischemic stroke (AIS). In total 15,792 academic papers about S-100B protein and AIS were reviewed, showing a sharp incline in publications after 1980. Leading the publications of research and citations were the United States, followed by Japan and Germany, which also had the highest clustered connections as well. The most prevalent organization was the Harvard University. This bibliometric analysis aims to analyze the prognostic value of S-100B protein as a potential biomarker in AIS with global data.
对1965年至2025年期间以S-100B蛋白和急性缺血性中风（AIS）为重点的学术研究进行了文献计量分析。总共审查了15792篇关于S-100B蛋白和AIS的学术论文，结果显示1980年之后的出版物数量急剧上升。在研究出版物和引用方面领先的是美国，其次是日本和德国，它们的聚类连接也最多。最主要的机构是哈佛大学。这项文献计量分析旨在利用全球数据分析S-100B蛋白作为AIS潜在生物标志物的预后价值。
