Thapa Bikash Bikram, Thapa Suman, Thapa Narayan, Gurung Pratik Man Singh
Department of Surgery, Nepalese Army Institute of Health Sciences, College of Medicine (NAIHS-COM), Kathmandu, Nepal.
BMC Urol. 2025 Sep 26;25(1):238. doi: 10.1186/s12894-025-01934-0.
Percutaneous nephrolithotomy (PCNL) is the standard practice for the treatment of large renal stones. There has been a gradual shift from "standard" PCNL to increasingly less invasive forms of PCNL in recent years. Innovations in both the technology and techniques of PCNL continue to improve the safety and efficacy of renal stone surgery. Total tubeless mini-PCNL (TTmPCNL) is a minimally invasive form of PCNL where the risks and benefits are still under evaluation. The aim of this study was to assess the safety and efficacy of TTmPCNL.
This observational study was conducted in the Urology unit, Department of Surgery, Nepalese Army Institute of Health Sciences (NAIHS), from January 2025 to May 2025. All patients fulfilling the inclusion criteria (stone size 10-30 mm, no urinary tract infection, age ≥ 18 years) underwent prone TTmPCNL utilising pneumatic lithotripsy under fluoroscope guidance were enrolled in the study. Follow-up was performed to determine the stone-free rate (SFR), incidence of postoperative complications, and length of hospital stay.
A total of 44 TTmPCNL procedures were performed in patients aged 45.1 ± 13 years (mean ± standard deviation (SD)). The size of the renal stone was 19.7 ± 4.9 mm (mean ± SD). Stone complexity burden was assessed using Guy's stone scoring system (GSS). The postoperative decrease in haemoglobin was 1.32 ± 0.47 gm/dl (mean ± SD), the postoperative complication rate was 15.9%, and the SFR was 95.5%. The length of hospital stay was 1.5 ± 0.6 (mean ± SD) days. Significant differences in the stone-free rate (p = 0.02) and incidence of postoperative complications (0.008) were noted among different GSS groups.
TTmPCNL is a safe and effective surgical treatment option for the treatment of carefully selected renal stone disease, with an acceptable complication rate, short hospital stays, and high SFR.
经皮肾镜取石术(PCNL)是治疗大型肾结石的标准方法。近年来,从“标准”PCNL到侵入性越来越小的PCNL形式有逐渐转变的趋势。PCNL的技术和技巧方面的创新不断提高肾结石手术的安全性和有效性。完全无管迷你PCNL(TTmPCNL)是一种微创的PCNL形式,其风险和益处仍在评估中。本研究的目的是评估TTmPCNL的安全性和有效性。
本观察性研究于2025年1月至2025年5月在尼泊尔军队卫生科学研究所(NAIHS)外科泌尿外科进行。所有符合纳入标准(结石大小10 - 30毫米,无尿路感染,年龄≥18岁)的患者在荧光镜引导下采用气压弹道碎石术进行俯卧位TTmPCNL,均纳入本研究。进行随访以确定结石清除率(SFR)、术后并发症发生率和住院时间。
共对年龄为45.1±13岁(平均±标准差(SD))的患者进行了44例TTmPCNL手术。肾结石大小为19.7±4.9毫米(平均±SD)。使用盖伊结石评分系统(GSS)评估结石复杂程度。术后血红蛋白下降1.32±0.47克/分升(平均±SD),术后并发症发生率为15.9%,结石清除率为95.5%。住院时间为1.5±0.6(平均±SD)天。不同GSS组之间在结石清除率(p = 0.02)和术后并发症发生率(0.008)方面存在显著差异。
对于精心挑选的肾结石疾病,TTmPCNL是一种安全有效的手术治疗选择,具有可接受的并发症发生率、较短的住院时间和较高的结石清除率。