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完全无管经皮肾镜取石术对于复杂性结石病是一种安全有效的选择吗?

Is Totally Tubeless Percutaneous Nephrolithotomy a Safe and Efficacious Option for Complex Stone Disease?

作者信息

Tomer Nir, Durbhakula Vinay, Gupta Kavita, Khargi Raymond, Gallante Blair, Atallah William M, Gupta Mantu

机构信息

Department of Urology, Icahn School of Medicine at Mount Sinai, 425 W. 59th Street, Suite 4F, New York, NY 10019, USA.

出版信息

J Clin Med. 2024 May 31;13(11):3261. doi: 10.3390/jcm13113261.

DOI:10.3390/jcm13113261
PMID:38892972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11173244/
Abstract

: Percutaneous nephrolithotomy is the gold standard treatment for large, complex intrarenal stones. Historically, this was performed using a nephrostomy tube (PCN) and/or internalized ureteral stent at the end of the procedure. However, totally tubeless nephrolithotomy (tt-PCNL) is a novel technique where no tubes (no stent nor nephrostomy tube) are left post-operatively. We review the literature on this subject regarding peri-operative outcomes, post-operative outcomes, and potential complications of the procedure, discuss our technique, and make recommendations on implementation for centers not currently utilizing the procedure. : We performed a comprehensive search of the literature on totally tubeless nephrolithotomy using MEDLINE database search. Our search included prior review articles, meta-analyses, systematic reviews, primary research articles, case reports, and case studies. : In comparison to prior approaches where a stent or nephrostomy tube is placed, tt-PCNL has a similar complication rate and better post-operative outcomes. Totally tubeless PCNL has similar operative times and similar changes in hemoglobin. However, it had shorter length of stays across all studies. The mean difference in length of stay in the studies reviewed was 1.96 days. Additionally, tt-PCNL had decreased post-operative analgesic requirements and pain scores. : This review highlights totally tubeless percutaneous nephrolithotomy as a safe and feasible surgical technique with improved outcomes in properly selected patients.

摘要

经皮肾镜取石术是治疗大型复杂肾内结石的金标准。从历史上看,该手术在结束时会使用肾造瘘管(PCN)和/或内置输尿管支架。然而,完全无管肾镜取石术(tt-PCNL)是一种新技术,术后不留任何管子(无支架也无肾造瘘管)。我们回顾了关于该手术围手术期结果、术后结果及潜在并发症的相关文献,讨论了我们的技术,并为目前未采用该手术的中心提出实施建议。:我们使用MEDLINE数据库搜索对完全无管肾镜取石术的文献进行了全面检索。我们的检索包括先前的综述文章、荟萃分析、系统评价、原始研究文章、病例报告和病例研究。:与先前放置支架或肾造瘘管的方法相比,tt-PCNL的并发症发生率相似,术后结果更好。完全无管PCNL的手术时间和血红蛋白变化相似。然而,在所有研究中其住院时间更短。所回顾研究中住院时间的平均差异为1.96天。此外,tt-PCNL术后镇痛需求和疼痛评分降低。:本综述强调完全无管经皮肾镜取石术是一种安全可行的手术技术,在适当选择的患者中能改善预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15b8/11173244/89318de7096f/jcm-13-03261-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15b8/11173244/89318de7096f/jcm-13-03261-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15b8/11173244/89318de7096f/jcm-13-03261-g001.jpg

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Totally tubeless, tubeless, and tubed percutaneous nephrolithotomy for treating kidney stones.完全无管化经皮肾镜取石术、无管化经皮肾镜取石术和有管化经皮肾镜取石术治疗肾结石。
Cochrane Database Syst Rev. 2023 Jul 28;7(7):CD012607. doi: 10.1002/14651858.CD012607.pub2.
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Advances in haemostatic sponges: Characteristics and the underlying mechanisms for rapid haemostasis.止血海绵的进展:快速止血的特性及潜在机制
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Complications and outcomes of tubeless versus nephrostomy tube in percutaneous nephrolithotomy: a systematic review and meta-analysis of randomized clinical trials.
经皮肾镜取石术中无管与肾造瘘管的并发症和结局:随机临床试验的系统评价和荟萃分析。
Urolithiasis. 2022 Oct;50(5):511-522. doi: 10.1007/s00240-022-01337-y. Epub 2022 Jun 8.
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Incidence of Kidney Stones in the United States: The Continuous National Health and Nutrition Examination Survey.美国肾结石的发病率:连续国家健康和营养检查调查。
J Urol. 2022 Apr;207(4):851-856. doi: 10.1097/JU.0000000000002331. Epub 2021 Dec 2.
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Ambulatory Percutaneous Nephrolithotomy in a Free-Standing Surgery Center: An Analysis of 500 Consecutive Cases.在独立的外科中心行门诊经皮肾镜取石术:500 例连续病例分析。
J Endourol. 2021 Dec;35(12):1738-1742. doi: 10.1089/end.2021.0159.
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Observational prospective study for surgical outcome and anesthetic feasibility of tubeless and totally tubeless supine PCNL: A single centre initial experience.无管及完全无管仰卧位经皮肾镜取石术手术结果及麻醉可行性的前瞻性观察研究:单中心初步经验
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Comparison of tubeless percutaneous nephrolithotomy and standard percutaneous nephrolithotomy for kidney stones: A meta-analysis of randomized trials.无管经皮肾镜取石术与标准经皮肾镜取石术治疗肾结石的比较:一项随机试验的荟萃分析。
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