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Brucellosis.布鲁氏菌病
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A Systematic Review and Meta-Analysis of Epidemiology and Clinical Manifestations of Human Brucellosis in China.一项中国布鲁氏菌病流行病学和临床表现的系统评价和荟萃分析。
Biomed Res Int. 2018 Apr 22;2018:5712920. doi: 10.1155/2018/5712920. eCollection 2018.
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Association of brucellosis with renal tubular and glomerular damage in children in Turkey.
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Clinical and laboratory features, complications and treatment outcome of brucellosis in childhood and review of the literature.儿童布鲁氏菌病的临床和实验室特征、并发症及治疗结果并文献复习
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Vet Immunol Immunopathol. 2011 May 15;141(1-2):58-63. doi: 10.1016/j.vetimm.2011.02.005. Epub 2011 Feb 18.
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中国一例伴有肾周炎的布鲁氏菌病表现为腹痛和腰痛。

A case of brucellosis with perinephritis presented as abdominal and low back pain in China.

作者信息

Li Hang, Gao Xiang, Li Zi-Yang, Xu Xia, Chen Jian-Ping

机构信息

Department of Pain, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi 030032, China.

Department of Laboratory Medicine, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi 030032, China.

出版信息

IDCases. 2025 Sep 15;42:e02372. doi: 10.1016/j.idcr.2025.e02372. eCollection 2025.

DOI:10.1016/j.idcr.2025.e02372
PMID:41017835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12466157/
Abstract

BACKGROUND

Human brucellosis, a zoonotic infection, typically manifests as fever, fatigue, anorexia, and osteoarticular pain. We report a rare case of brucellosis complicated by perinephritis, presenting with abdominal and low back pain.

CASE PRESENTATION

A 74-year-old male presented with fever, abdominal and low back pain. Initial lumbar magnetic resonance imaging (MRI) demonstrated L4-5 disc herniation with foraminal and spinal canal stenosis, while abdominal computed tomography (CT) revealed perinephric inflammation without structural abnormalities. Upon developing intermittent fever (38 °C), epidemiological history uncovered chronic consumption of uninspected sheep meat. Brucellosis with perinephritis was confirmed via supportive agglutination test and blood culture.

CONCLUSIONS

Perinephritis is an uncommon complication of brucellosis, and atypical abdominal pain warrants consideration of zoonotic exposure. Serological testing (agglutination test) and blood culture remain critical for timely diagnosis in high-risk patients.

摘要

背景

人类布鲁氏菌病是一种人畜共患感染病,典型症状为发热、疲劳、厌食和骨关节疼痛。我们报告一例罕见的布鲁氏菌病并发肾周炎病例,表现为腹痛和腰痛。

病例介绍

一名74岁男性患者出现发热、腹痛和腰痛症状。最初的腰椎磁共振成像(MRI)显示L4-5椎间盘突出伴椎间孔和椎管狭窄,而腹部计算机断层扫描(CT)显示肾周炎症但无结构异常。在出现间歇性发热(38°C)后,流行病学史显示患者长期食用未经检验的羊肉。通过支持性凝集试验和血培养确诊为布鲁氏菌病并发肾周炎。

结论

肾周炎是布鲁氏菌病的一种罕见并发症,非典型腹痛应考虑人畜共患感染暴露。血清学检测(凝集试验)和血培养对于高危患者的及时诊断仍然至关重要。