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累及颅底的青少年鼻咽血管纤维瘤:对典型青少年表现的影像学和临床洞察

Juvenile Nasopharyngeal Angiofibroma With Skull Base Involvement: A Radiological and Clinical Insight Into a Classic Adolescent Presentation.

作者信息

Labbi Zineb, Boukhlouf Oumaima, Fikri Meriem, Jiddane Mohammed, Touarsa Firdaous

机构信息

Department of Diagnostic Radiology, Ibn Sina University Hospital, Rabat, MAR.

Department of Maxillofacial Surgery, Ibn Sina University Hospital, Mohammed V University, Rabat, MAR.

出版信息

Cureus. 2025 Aug 28;17(8):e91191. doi: 10.7759/cureus.91191. eCollection 2025 Aug.

DOI:10.7759/cureus.91191
PMID:41018324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12476233/
Abstract

Juvenile nasopharyngeal angiofibroma (JNA) represents a rare, histologically benign yet locally aggressive vascular tumor that predominantly arises in adolescent males. Given its propensity for invasive growth and involvement of critical anatomical structures, precise radiological evaluation is vital prior to any intervention. We present the case of a 13-year-old male who experienced progressive bilateral nasal blockage and recurrent epistaxis predominantly on the left side. Magnetic resonance imaging (MRI) identified a vividly enhancing lesion centered at the left sphenopalatine foramen, with extensions into adjacent sinuses, the pterygopalatine fossa, infratemporal fossa, and early skull base erosion. This case highlights the critical diagnostic and staging role of MRI in JNA, illustrating how characteristic imaging findings inform diagnosis, classification, and surgical planning.

摘要

青少年鼻咽血管纤维瘤(JNA)是一种罕见的、组织学上为良性但具有局部侵袭性的血管肿瘤,主要发生于青春期男性。鉴于其有侵袭性生长的倾向并累及重要解剖结构,在进行任何干预之前,精确的放射学评估至关重要。我们报告一例13岁男性病例,该患者主要表现为进行性双侧鼻塞,以左侧为主,并反复鼻出血。磁共振成像(MRI)显示一个以左侧蝶腭孔为中心的明显强化病变,病变延伸至相邻鼻窦、翼腭窝、颞下窝,并早期侵犯颅底。该病例突出了MRI在JNA诊断和分期中的关键作用,展示了典型的影像学表现如何为诊断、分类和手术规划提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c600/12476233/6763e56ee16e/cureus-0017-00000091191-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c600/12476233/b81a7a0a7656/cureus-0017-00000091191-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c600/12476233/4e6ef78d2e40/cureus-0017-00000091191-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c600/12476233/6763e56ee16e/cureus-0017-00000091191-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c600/12476233/b81a7a0a7656/cureus-0017-00000091191-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c600/12476233/4e6ef78d2e40/cureus-0017-00000091191-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c600/12476233/6763e56ee16e/cureus-0017-00000091191-i03.jpg

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本文引用的文献

1
Juvenile Nasopharyngeal Angiofibroma: A Case Study on the Diagnostic and Surgical Challenges in an Adolescent Male.青少年鼻咽血管纤维瘤:一名青少年男性诊断与手术挑战的病例研究
Cureus. 2024 Jun 4;16(6):e61667. doi: 10.7759/cureus.61667. eCollection 2024 Jun.
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Nasopharyngeal Carcinoma in Children, Current Treatment Approach.儿童鼻咽癌:当前的治疗方法。
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Early-onset juvenile nasopharyngeal angiofibroma (JNA): a systematic review.
早发性青少年鼻咽血管纤维瘤(JNA):系统评价。
J Otolaryngol Head Neck Surg. 2023 Dec 19;52(1):85. doi: 10.1186/s40463-023-00687-w.
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MRI features of sinonasal tract angiofibroma/juvenile nasopharyngeal angiofibroma: Case series and systematic review.鼻窦血管纤维瘤/青少年鼻咽血管纤维瘤的MRI特征:病例系列及系统评价
J Neuroimaging. 2023 Sep-Oct;33(5):675-687. doi: 10.1111/jon.13116. Epub 2023 May 10.
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