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Mechanism insights and therapeutic intervention of tumor metastasis: latest developments and perspectives.肿瘤转移的机制洞察与治疗干预:最新进展与展望
Signal Transduct Target Ther. 2024 Aug 2;9(1):192. doi: 10.1038/s41392-024-01885-2.
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Incidence rate of metastases in the oral cavity: a review of all metastatic lesions in the oral cavity.口腔转移瘤的发生率:对所有口腔转移病变的回顾。
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Two rare cases of oral metastasis arising from lung adenocarcinoma and esophageal carcinoma.两例罕见的由肺腺癌和食管癌引起的口腔转移病例。
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J Clin Periodontol. 2009 Jun;36(6):488-92. doi: 10.1111/j.1600-051X.2009.01407.x.

口腔转移作为晚期肺腺癌的先兆:一例罕见且病情迅速恶化的病例研究

Oral Metastasis as a Harbinger of Terminal Lung Adenocarcinoma: A Case Study of Rare and Rapid Decline.

作者信息

Aslam Shehroz, Onwumere Nnenna M, Akram Hamzah, Riaz Rida, Burza Aaliya

机构信息

Internal Medicine, Samaritan Medical Center, Watertown, USA.

Internal Medicine, Hamilton Health Science, Hamilton, CAN.

出版信息

Cureus. 2025 Aug 26;17(8):e91065. doi: 10.7759/cureus.91065. eCollection 2025 Aug.

DOI:10.7759/cureus.91065
PMID:41018427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12463548/
Abstract

Lung cancer is one of the most prevalent cancers in the United States (U.S), with adenocarcinoma representing the most predominant subtype. Metastasis to the oral cavity from lung adenocarcinoma is exceedingly rare. This case report describes a patient with lung adenocarcinoma who developed oral metastases, presenting as exophytic lesions along the right maxillary and left mandibular alveolar ridges. The prognostic implications of such metastases are not well-reported in the literature due to the limited number of cases. This case highlights the crucial importance of timely evaluation of oral lesions in patients with known malignancies to facilitate early diagnosis, guide treatment, and improve prognostication and symptom management.

摘要

肺癌是美国最常见的癌症之一,其中腺癌是最主要的亚型。肺腺癌转移至口腔极为罕见。本病例报告描述了一名患有肺腺癌并发生口腔转移的患者,表现为沿右上颌和左下颌牙槽嵴的外生性病变。由于病例数量有限,此类转移的预后影响在文献中报道较少。本病例强调了对已知恶性肿瘤患者的口腔病变进行及时评估的至关重要性,以便促进早期诊断、指导治疗并改善预后和症状管理。