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两例罕见的由肺腺癌和食管癌引起的口腔转移病例。

Two rare cases of oral metastasis arising from lung adenocarcinoma and esophageal carcinoma.

作者信息

Rocha Breno-Amaral, Paranaíba Lívia-Maris-Ribeiro, Dantas Ciro-Dantas, de Carvalho Maria-Goretti-Freire, de Melo-Filho Mário-Rodrigues, Lima Lucianne-Maia-Costa, Souto Giovanna-Ribeiro, Horta Martinho-Campolina-Rebello

机构信息

Graduate Program in Dentistry, School of Dentistry, Pontifícia Universidade Católica de Minas Gerais (PUC Minas), Belo Horizonte, Minas Gerais, Brazil.

Department of Pathology and Parasitology, Institute of Biomedical Sciences, Federal University of Alfenas, Alfenas, MG, Brazil.

出版信息

J Clin Exp Dent. 2020 Oct 1;12(10):e999-e1004. doi: 10.4317/jced.57125. eCollection 2020 Oct.

DOI:10.4317/jced.57125
PMID:33154803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7600200/
Abstract

Metastasis to the oral cavity are rare, representing only 1% of all oral malignancies, and originate from various sites such as the breast, prostate, lung and kidney. Clinically, they can simulate reactive and inflammatory lesions common in the oral cavity, and the clinical and microscopic diagnosis of these metastasis is a challenge. In this article, we report two new cases of esophageal and lung metastasis to oral tissues, highlighting their clinical characteristics and the process of diagnostic elucidation. We emphasize the importance for clinicians to consider the possibility of metastatic lesions in the oral cavity in patients previously diagnosed with malignant lesions in distant tissues and organs. Diagnosis, esophageal squamous cell carcinoma, adenocarcinoma of lung, oral cavity, metastasis.

摘要

口腔转移瘤较为罕见,仅占所有口腔恶性肿瘤的1%,其原发部位多样,如乳腺、前列腺、肺和肾脏等。临床上,它们可能类似口腔常见的反应性和炎性病变,对这些转移瘤进行临床及显微镜诊断颇具挑战。在本文中,我们报告了两例食管和肺转移至口腔组织的新病例,重点阐述了其临床特征及诊断思路。我们强调临床医生对于先前被诊断为远处组织和器官恶性病变的患者,应考虑口腔出现转移瘤的可能性。诊断:食管鳞状细胞癌、肺腺癌、口腔、转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9494/7600200/cc3807bee7ca/jced-12-e999-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9494/7600200/9894b6cc399b/jced-12-e999-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9494/7600200/080d716410f3/jced-12-e999-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9494/7600200/cc3807bee7ca/jced-12-e999-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9494/7600200/9894b6cc399b/jced-12-e999-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9494/7600200/080d716410f3/jced-12-e999-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9494/7600200/cc3807bee7ca/jced-12-e999-g003.jpg

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本文引用的文献

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Esophageal Cancer Metastases to Unexpected Sites: A Systematic Review.食管癌转移至意外部位:一项系统综述
Gastroenterol Res Pract. 2017;2017:1657310. doi: 10.1155/2017/1657310. Epub 2017 Jun 4.
2
Metastasis to the Jawbones: A review of 453 cases.颌骨转移:453例病例回顾
J Int Soc Prev Community Dent. 2017 Mar-Apr;7(2):71-81. doi: 10.4103/jispcd.JISPCD_512_16. Epub 2017 Mar 29.
3
Non-small-cell lung cancer metastasis to the oral cavity: A case report.非小细胞肺癌转移至口腔:一例报告。
食管鳞状细胞癌转移至口腔:一例报告及文献综述
Ann Med Surg (Lond). 2023 Jul 15;85(9):4603-4607. doi: 10.1097/MS9.0000000000001086. eCollection 2023 Sep.
Mol Clin Oncol. 2017 Mar;6(3):422-424. doi: 10.3892/mco.2017.1141. Epub 2017 Jan 31.
4
Metastatic tumors in the jaw bones: A retrospective clinicopathological study of 12 cases at Tertiary Cancer Center.颌骨转移性肿瘤:在三级癌症中心对12例病例的回顾性临床病理研究
J Oral Maxillofac Pathol. 2016 May-Aug;20(2):252-5. doi: 10.4103/0973-029X.185920.
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Unusual Presentation of an Adenocarcinoma of the Lung Metastasizing to the Mandible, Including Molecular Analysis and a Review of the Literature.一例肺腺癌转移至下颌骨的罕见表现,包括分子分析及文献复习
J Oral Maxillofac Surg. 2016 Oct;74(10):2007.e1-8. doi: 10.1016/j.joms.2016.06.004. Epub 2016 Jun 12.
6
Metastatic solid tumors to the jaw and oral soft tissue: A retrospective clinical analysis of 44 patients from a single institution.转移至颌骨及口腔软组织的实体瘤:来自单一机构的44例患者的回顾性临床分析
J Craniomaxillofac Surg. 2016 Aug;44(8):1047-53. doi: 10.1016/j.jcms.2016.05.013. Epub 2016 May 15.
7
Metastatic tumors to the jaws and mouth.转移至颌骨和口腔的肿瘤。
Head Neck Pathol. 2014 Dec;8(4):463-74. doi: 10.1007/s12105-014-0591-z. Epub 2014 Nov 20.
8
Metastatic tumors of the oral cavity.口腔转移性肿瘤。
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Head Neck Pathol. 2013 Dec;7(4):416-20. doi: 10.1007/s12105-013-0450-3. Epub 2013 Jun 6.