Kazemian Navid, Khorami Mozhgan, Grillo Ricardo, Hashemzadeh Haleh, Bardideh Erfan, Family Khashayar, Ebrahimpour Alireza, Samieirad Sahand
Student Research Committee, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Oral and Maxillofacial Surgery, University of São Paulo, São Paulo, Brazil.
World J Plast Surg. 2025;14(2):72-78. doi: 10.61186/wjps.14.2.72.
Alveolar osteitis (AO), commonly known as dry socket, is a recognized complication following tooth extraction, particularly prevalent after mandibular third molar extractions. Given the global pandemic of coronavirus disease (COVID-19) and its implications for endothelial and hematologic changes, investigating its potential impact on dry socket risk in patients undergoing mandibular third molar extraction is crucial.
We reviewed patient records from individuals undergoing mandibular third molar extraction at Mashhad Dental School, Mashhad, Iran in 2022. Data included demographics, medical history, smoking status, and COVID-19 details such as history, hospitalization, and vaccination status.
Clinical examinations diagnosed alveolar osteitis, assessing for blood clot presence and local lymphadenitis. Out of 119 patients (82 females, 37 males), 49.6% developed dry socket post-extraction, with 94.1% having a history of COVID-19 and 32.7% requiring hospitalization due to the disease. 97.5% of patients were vaccinated against COVID-19. Additionally, 44.5% had systemic disease history, and 45.4% used related medications, with no observed associations with dry socket.
This study underscores the increased risk of dry socket following mandibular third molar extraction associated with corticosteroid use, oral contraceptive use, smoking, and COVID-19 hospitalization. Females exhibited a significantly higher risk compared to males. While no significant COVID-19 infection-dry socket link was found, the study highlights the need for further research, given the significant number of dry socket cases among COVID-19 patients and those hospitalized due to COVID-19.
牙槽骨炎(AO),通常称为干槽症,是拔牙后公认的并发症,在下颌第三磨牙拔除后尤为常见。鉴于冠状病毒病(COVID-19)的全球大流行及其对内皮和血液学变化的影响,研究其对接受下颌第三磨牙拔除术患者发生干槽症风险的潜在影响至关重要。
我们回顾了2022年在伊朗马什哈德牙科学校接受下颌第三磨牙拔除术患者的病历。数据包括人口统计学、病史、吸烟状况以及COVID-19的详细信息,如病史、住院情况和疫苗接种状况。
临床检查诊断牙槽骨炎,评估血凝块存在情况和局部淋巴结炎。在119名患者(82名女性,37名男性)中,49.6%在拔牙后发生干槽症,94.1%有COVID-19病史,32.7%因该疾病需要住院治疗。97.5%的患者接种了COVID-19疫苗。此外,44.5%有全身疾病史,45.4%使用相关药物,未观察到与干槽症的关联。
本研究强调下颌第三磨牙拔除术后发生干槽症的风险增加与使用皮质类固醇、口服避孕药、吸烟以及COVID-19住院治疗有关。女性的风险明显高于男性。虽然未发现COVID-19感染与干槽症之间有显著联系,但鉴于COVID-19患者和因COVID-19住院患者中干槽症病例数量众多,该研究强调需要进一步研究。