枯草芽孢杆菌细胞质膜缺陷突变体产生抗生素的研究。

Antibiotic production by defective cytoplasmic membrane mutants of Bacillus subtilis.

作者信息

Perez-Silva G, Gil I, Rodriguez D

出版信息

Zentralbl Bakteriol Parasitenkd Infektionskr Hyg. 1977;132(4):289-93. doi: 10.1016/s0044-4057(77)80016-6.

Abstract

Eleven defective cytoplasmic membrane mutants of Bacillus subtilis were isolated. Their respective protoplasts presented different lytic behaviour when exposed to decreased concentrations of sucrose. Some relationship was found between the fragility of the protoplasts and the capacity of the mutants to produce antibiotic or to sporulate. The higher the fragility the lesser the capacity to produce antibiotic. The same applies to their amino acids requirements.

摘要

分离出了枯草芽孢杆菌的11个有缺陷的细胞质膜突变体。当暴露于浓度降低的蔗糖中时，它们各自的原生质体表现出不同的裂解行为。在原生质体的脆弱性与突变体产生抗生素或形成芽孢的能力之间发现了一些关系。原生质体的脆弱性越高，产生抗生素的能力就越低。这同样适用于它们对氨基酸的需求。