Katz Jason B, Kalluri Aravind, Leya Marysa, Cremer Paul C, Johnston Douglas R, Al-Kazaz Mohamed, Schimmel Daniel R
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Division of Cardiology, Department of Medicine, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
J Soc Cardiovasc Angiogr Interv. 2025 Jul 23;4(8):103800. doi: 10.1016/j.jscai.2025.103800. eCollection 2025 Aug.
Pericardial effusions can occur owing to a variety of reasons such as trauma, infection, autoimmune disease, and malignancy. Cardiac tamponade depends on the rate of fluid accumulation and not solely on the volume of the pericardial effusion. Rapid accumulation of pericardial fluid can lead to impaired cardiac filling and output with hemodynamic consequences, requiring urgent or emergent intervention. Despite initial intervention on patients with cardiac tamponade, recurrence of pericardial effusions has been estimated at approximately 20%, with a mean interval to recurrence of approximately 1 month. Both interventional and surgical techniques have been developed to relieve excess pericardial fluid including pericardiocentesis, surgical pericardiotomy, and percutaneous balloon pericardiotomy (PBP) with the latter 2 generally reserved for recurrent effusions. Rarely, surgical pericardiectomy is pursued. While safety and outcomes data are readily available for both pericardiocentesis and surgical pericardiotomies, PBPs are performed less frequently and at the few medical centers with the necessary expertise. In this case series, we present our center's experience with PBP in the management of recurrent pericardial effusions in 4 different patients. We highlight their comorbidities and corresponding high surgical risk as well as review the technical considerations and outcomes of each patient. Aside from a small pneumothorax managed conservatively, there were no adverse side effects encountered. Balloon pericardiotomy is a safe and effective modality for pericardial effusion drainage in high-risk patients, which can improve patient comfort and hemodynamics.
心包积液可由于多种原因发生,如创伤、感染、自身免疫性疾病和恶性肿瘤。心脏压塞取决于液体的积聚速度,而不仅仅取决于心包积液的量。心包积液的快速积聚可导致心脏充盈和输出受损,产生血流动力学后果,需要紧急或急诊干预。尽管对心脏压塞患者进行了初始干预,但据估计心包积液的复发率约为20%,平均复发间隔约为1个月。已经开发了介入和手术技术来缓解过多的心包积液,包括心包穿刺术、外科心包切开术和经皮球囊心包切开术(PBP),后两者通常用于复发性积液。很少进行外科心包切除术。虽然心包穿刺术和外科心包切开术的安全性和结果数据很容易获得,但PBP的实施频率较低,且仅在少数具备必要专业知识的医疗中心进行。在这个病例系列中,我们介绍了我们中心对4例不同患者采用PBP治疗复发性心包积液的经验。我们强调了他们的合并症和相应的高手术风险,并回顾了每位患者的技术考虑因素和结果。除了少量气胸采取保守治疗外,未出现不良副作用。球囊心包切开术对于高危患者的心包积液引流是一种安全有效的方式,可改善患者的舒适度和血流动力学。