Kudrinskiy Alexey Viktorovich, Snitsar Artem Vladimirovich, Sedgaryan Marat Amayakovich, Patlachuk Maxim Valentinovich
State Budgetary Healthcare Institution of the City of Moscow "City Clinical Hospital named after M.E. Zhadkevich of the Healthcare Department of the City of Moscow", Moscow, 121374, Mozhaiskoe Highway, 14, Russia.
State Budgetary Healthcare Institution of the City of Moscow "City Clinical Hospital №24 of the Healthcare Department of the City of Moscow", Moscow, 127015, Pistsovaya St., 10, building 2, Russia.
Radiol Case Rep. 2025 Sep 15;20(12):5994-6002. doi: 10.1016/j.radcr.2025.08.056. eCollection 2025 Dec.
We describe a case of severe coronary artery stenosis in a 29-year-old male 1 month after aortic root replacement (ARR). The patient presented with exertional chest pain that progressed to prolonged resting angina and ventricular arrhythmia. Electrocardiography showed ischemic changes suggestive of left coronary artery involvement, and multislice computed tomography angiography confirmed subtotal stenosis at the left main (LM) bifurcation. Urgent percutaneous coronary intervention (PCI) with drug-eluting stent implantation from the LM to the left anterior descending artery was performed using a provisional technique, resulting in improvement of left ventricular ejection fraction from 23% to 55%. The patient was discharged without complications and remained event-free at 6-month follow-up. This case highlights a rare but potentially life-threatening coronary complication after ARR, which may be related to perfusion cannula placement, technical factors during coronary ostial reimplantation, or proliferative reactions to the aortic prosthesis or gelatin-resorcinol-formaldehyde glue. It underscores the need for early recognition and vigilance for coronary ischemia after ARR - even in young patients without prior coronary artery disease - and emphasizes the efficacy of emergency PCI. A multidisciplinary approach is recommended to optimize outcomes in complex postsurgical cardiovascular patients.
我们描述了一例29岁男性在主动脉根部置换术(ARR)后1个月出现严重冠状动脉狭窄的病例。该患者最初表现为劳力性胸痛,随后进展为持续性静息性心绞痛和室性心律失常。心电图显示有提示左冠状动脉受累的缺血性改变,多层螺旋计算机断层扫描血管造影证实左主干(LM)分叉处次全狭窄。采用临时技术从LM至左前降支进行了紧急经皮冠状动脉介入治疗(PCI)并植入药物洗脱支架,左心室射血分数从23%提高到了55%。患者出院时无并发症,6个月随访时无不良事件发生。该病例突出了ARR后一种罕见但可能危及生命的冠状动脉并发症,其可能与灌注插管的放置、冠状动脉开口再植入期间的技术因素、或对主动脉假体或明胶-间苯二酚-甲醛胶水的增殖反应有关。它强调了即使在没有既往冠状动脉疾病的年轻患者中,ARR后也需要早期识别并警惕冠状动脉缺血,同时强调了紧急PCI的有效性。建议采用多学科方法以优化复杂术后心血管患者的治疗效果。