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血管内碎石术辅助治疗重度钙化病变的颈动脉支架置入术:病例系列

Intravascular lithotripsy-assisted carotid artery stenting in heavily calcified lesions: A case series.

作者信息

Diaz Orlando, Gerstner Saucedo Jochen, Carmona Isabel, Lumsden Alan B, Lengyel Balazs C

机构信息

Department of Radiology, Houston Methodist Hospital, 6565 Fannin Street, Houston, TX 77030, USA.

Advanced Imaging Lab, Department of Radiology, University of Colorado Anschutz Medical Campus, 13001 East 17th Place, Aurora, CO 80045, USA.

出版信息

Radiol Case Rep. 2025 Sep 15;20(12):5977-5983. doi: 10.1016/j.radcr.2025.08.087. eCollection 2025 Dec.

DOI:10.1016/j.radcr.2025.08.087
PMID:41019966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12464689/
Abstract

Intravascular lithotripsy (IVL), although considered off-label for carotid interventions, has proven to be beneficial for the treatment of heavily calcified lesions and may improve outcomes in select patients unsuitable for open repair. We present 3 consecutive cases of IVL-assisted carotid artery stenting (CAS) performed via transfemoral and transradial approaches in patients with severe internal carotid artery calcification. All patients were considered poor candidates for carotid endarterectomy (CEA). Technical success was achieved in all cases, with no neurological complications noted during the perioperative period, 30-day follow-up (with 6-month follow-up in 2 patients since 1 was lost to follow-up). All procedures were performed using distal filter protection alone without flow reversal, in contrast to most published series. IVL may broaden CAS applicability for patients with circumferential calcification and combined high anatomic/physiologic surgical risk who are not candidates for CEA. Further studies are warranted to evaluate long-term outcomes and optimal patient selection.

摘要

血管内碎石术(IVL)虽被视为颈动脉介入治疗的非适应证,但已证明对治疗严重钙化病变有益,且可能改善某些不适合开放修复患者的治疗效果。我们展示了3例连续通过股动脉和桡动脉途径进行IVL辅助颈动脉支架置入术(CAS)的病例,这些患者存在严重的颈内动脉钙化。所有患者均被认为不适合进行颈动脉内膜切除术(CEA)。所有病例均取得技术成功,围手术期未出现神经并发症,随访30天(2例患者随访6个月,1例失访)。与大多数已发表的系列研究不同,所有手术均仅使用远端滤网保护而未进行血流逆转。IVL可能会扩大CAS对那些存在环形钙化且解剖/生理手术风险高而不适合CEA的患者的适用性。有必要进行进一步研究以评估长期疗效和最佳患者选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0571/12464689/4b49a3f62d88/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0571/12464689/5751d93da7f7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0571/12464689/d225d67544fe/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0571/12464689/4b49a3f62d88/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0571/12464689/5751d93da7f7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0571/12464689/d225d67544fe/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0571/12464689/4b49a3f62d88/gr3.jpg

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本文引用的文献

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Adjunctive intravascular lithotripsy for heavily calcified carotid stenosis: a dual-center experience and technical case series.辅助血管内碎石术治疗重度钙化性颈动脉狭窄:双中心经验及技术病例系列
J Neurointerv Surg. 2025 Jan 27. doi: 10.1136/jnis-2024-022545.
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Multi-center experience with intravascular lithotripsy for treatment of severe calcification during transcarotid artery revascularization for high-risk patients.
多中心经验:血管内碎石术治疗高危患者经颈动脉血运重建术时的严重钙化。
J Vasc Surg. 2024 Sep;80(3):757-763. doi: 10.1016/j.jvs.2024.04.049. Epub 2024 May 20.
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Rotational Atherectomy, Orbital Atherectomy, and Intravascular Lithotripsy Comparison for Calcified Coronary Lesions.钙化冠状动脉病变的旋磨术、轨道旋切术和血管内冲击波碎石术比较
J Clin Med. 2023 Nov 23;12(23):7246. doi: 10.3390/jcm12237246.
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Intravascular Lithotripsy Assisted Carotid Stent Expansion.血管内碎石术辅助颈动脉支架扩张术。
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Carotid Artery Plaque Calcifications: Lessons From Histopathology to Diagnostic Imaging.颈动脉斑块钙化:从组织病理学到诊断影像学的启示。
Stroke. 2022 Jan;53(1):290-297. doi: 10.1161/STROKEAHA.121.035692. Epub 2021 Nov 10.
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