Bauer L
Zentralbl Bakteriol Orig B. 1977 Aug;164(5-6):455-68.
Several bands of dish detergents were found in high dilutions to increase phototoxic cell damage produced by polycyclic hydrocarbons such as benzo(a)pyrene. A comparable increase in phototoxicity in the presence of detergents was observed following the phagocytic ingestion of photodynamically active soot particles by the test organisms, Tetrahymena pyriformis (ciliate). The results are considered in the light of earlier reports on increased carcinogenicity following detergent action of one of the brands used in this investigation (P) on benzo(a)-pyrene. Possible mechanisms of action of detergents producing the increase in respective activities are discussed.
研究发现,几种餐具洗涤剂在高稀释度下会增加多环芳烃(如苯并(a)芘)所产生的光毒性细胞损伤。在用受试生物梨形四膜虫(纤毛虫)对具有光动力活性的烟尘颗粒进行吞噬摄取后,观察到洗涤剂存在时光毒性有类似增加。根据此前关于本研究中使用的一个品牌洗涤剂(P)对苯并(a)芘作用后致癌性增加的报告,对这些结果进行了考量。讨论了洗涤剂导致各自活性增加的可能作用机制。