Quian Anna, Mercier Ann Marie, Akers Allison, Wenham Robert M, Chon Hye Sook, Shahzad Mian M, Chern Jing-Yi, Mhaskar Rahul, Hoffman Mitchel
Department of Gynecologic Oncology, Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL, 33612, USA.
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Icahn School of Medicine at Mount Sinai, 1176 Fifth Ave Box 1170, New York, NY, 10029, USA.
J Robot Surg. 2025 Oct 18;19(1):699. doi: 10.1007/s11701-025-02889-y.
This study investigates methods of specimen extraction, pertinent clinical data and pathologic findings associated with minimally invasive surgery (MIS) for adnexal masses. This retrospective cohort study includes patients with an adnexal mass who underwent MIS removal. The association of categorical variables with adverse outcomes was investigated using Pearson chi-square or Fisher's exact test. Four hundred and thirty-eight patients met inclusion criteria. Surgical modalities included laparoscopic (n = 235, 53.7%), robotic (n = 165, 37.7%), and vaginal (n = 1, 0.2%). MIS was converted to laparotomy in 37 cases (8.4%). 203 (46.3%) specimens were removed vaginally, and 235 (53.7%) abdominally. Three hundred and nineteen (72.8%) specimens were removed intact whereas 119 (27.2%) were morcellated or drained 113 contained). Of the 6 uncontained morcellation cases, one was ovarian cancer, and one was a borderline tumor. For malignant histologies, receipt of adjuvant chemotherapy was not associated with specimen integrity (455 intact vs 12 morcellated, p = 0.207), route of specimen removal (31 vaginal vs 36 abdominal, p = 0.217), or use of a specimen bag (46 bag vs 21 no bag, p = 0.105). This study demonstrated that MIS is feasible in the majority of patients referred to our cancer center for an adnexal mass. Perioperative complications were uncommon. Management of the ovarian malignancies encountered in this cohort was not compromised by utilization of MIS.
本研究调查了附件包块微创手术(MIS)相关的标本提取方法、相关临床数据及病理结果。这项回顾性队列研究纳入了接受MIS切除附件包块的患者。采用Pearson卡方检验或Fisher精确检验研究分类变量与不良结局之间的关联。438例患者符合纳入标准。手术方式包括腹腔镜手术(n = 235,53.7%)、机器人手术(n = 165,37.7%)和阴道手术(n = 1,0.2%)。37例(8.4%)MIS转为开腹手术。203例(46.3%)标本经阴道取出,235例(53.7%)经腹部取出。319例(72.8%)标本完整取出,119例(27.2%)被切碎或引流(其中113例有内容物)。在6例未封闭切碎病例中,1例为卵巢癌,1例为交界性肿瘤。对于恶性组织学类型,接受辅助化疗与标本完整性(455例完整 vs 12例切碎,p = 0.207)、标本取出途径(31例经阴道 vs 36例经腹部,p = 0.217)或使用标本袋(46例使用 vs 21例未使用,p = 0.105)均无关。本研究表明,MIS在大多数转诊至我们癌症中心的附件包块患者中是可行的。围手术期并发症并不常见。该队列中遇到的卵巢恶性肿瘤的管理未因采用MIS而受到影响。