Budinger T F
Semin Nucl Med. 1977 Oct;7(4):285-97. doi: 10.1016/s0001-2998(77)80037-8.
Nuclear medicine instrumentation requires use of various configurations of photon detectors for the purpose of in vivo and in vitro measurements of flow and metabolism. Computed tomography has solved a previous limitation of an ambiguous volume of interest intrinsic to projection images. Selection of instruments involves first, a definition of the medical problem to be solved; then an evaluation of the following characteristics of the candidate instruments: sensitivity, spatial resolution, saturation performance, dead time, uniformity of resolution, uniformity of sensitivity, data processing capabilities, and cost. New developments include dynamic imaging in transverse section with either single photon or positron annihilation photons, and whole-body quantitative imaging of sequential changes in radiopharmaceutical concentration.
核医学仪器需要使用各种配置的光子探测器，以便在体内和体外测量血流与代谢。计算机断层扫描解决了投影图像固有的感兴趣体积模糊这一先前的局限性。仪器的选择首先要明确待解决的医学问题；然后评估候选仪器的以下特性：灵敏度、空间分辨率、饱和性能、死时间、分辨率均匀性、灵敏度均匀性、数据处理能力和成本。新的发展包括利用单光子或正电子湮灭光子进行横断面动态成像，以及对放射性药物浓度的连续变化进行全身定量成像。
