Buckman R F, Hufnagel H V, Olivier G, Buckman P D, Zuidema G D
Surgery. 1977 Nov;82(5):660-6.
An experimental study was performed in rhesus monkeys (M. mulatta) to examine the contribution of Bunnell tendon suture to the production of postoperative tendon adhesions. It was found that Bunnell suture used with atraumatic technique caused a significant depression of in vitro tendon surface plasminogen activator activity, allowing the in vivo persistence and fibrous organization of fibrinous postoperative adhesions to sutured areas. Bunnell suture also produced coagulation necrosis of the sutured area of tendon. Collagen, which replaced the destroyed areas, was oriented randomly and frequently was continuous with surface tendon adhesions to surrounding connective tissues. Bunnell suture appears to be a cause of tendon adhesions in subhuman primates. The importance of fibrin and depressed local fibrinolysis in the relationship of tendon ischemia and adhesion formation is discussed.
在恒河猴（猕猴）身上进行了一项实验研究，以检验邦内尔肌腱缝合术对术后肌腱粘连形成的影响。研究发现，采用无创伤技术使用邦内尔缝合线会导致体外肌腱表面纤溶酶原激活物活性显著降低，使得术后粘连在缝合区域的纤维蛋白在体内持续存在并形成纤维组织。邦内尔缝合线还会导致肌腱缝合区域发生凝固性坏死。取代受损区域的胶原蛋白排列随机，且常常与肌腱表面与周围结缔组织的粘连相连。邦内尔缝合线似乎是导致非人灵长类动物肌腱粘连的一个原因。文中讨论了纤维蛋白和局部纤溶功能降低在肌腱缺血与粘连形成关系中的重要性。
