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Cureus. 2025 Jul 16;17(7):e88066. doi: 10.7759/cureus.88066. eCollection 2025 Jul.
3
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eNeurologicalSci. 2025 Jul 22;40:100577. doi: 10.1016/j.ensci.2025.100577. eCollection 2025 Sep.
4
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颈性眼病:视觉症状和眼病的颈椎病因——探索颈部与眼睛关联机制的一种假说

Cervical Oculopathy: The Cervical Spine Etiology of Visual Symptoms and Eye Diseases-A Hypothesis Exploring Mechanisms Linking the Neck and the Eye.

作者信息

Hauser Ross A, Griffiths Morgan, Matias Danielle, Rawlings Benjamin R

机构信息

Caring Medical Florida, 9738 Commerce Center Court, Fort Myers, FL 33908, USA.

Independent Researcher, Fort Myers, FL 33908, USA.

出版信息

Diagnostics (Basel). 2025 Oct 21;15(20):2650. doi: 10.3390/diagnostics15202650.

DOI:10.3390/diagnostics15202650
PMID:41153322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12564055/
Abstract

Eye and visual symptoms are becoming increasingly common in young people, along with the emerging conditions text neck and computer vision syndrome, though underlying mechanisms are not fully elucidated. The link between cervical spine structure and the eye remains relatively unexplored. This paper employs a hypothesis-driven, literature-based evidence approach, aiming to explore the hypothesis that cervical spine structural issues may be an underlying mechanism for visual symptoms and eye diseases. The purpose of exploring this hypothesis is to lay the groundwork for future research, and advance diagnostics and treatment options. No new analysis was performed. This article lays the groundwork for the hypothesis that cervical spine structural dysfunctions, including a forward-displaced atlas (C1), can cause dynamic carotid sheath compression, contributing to neurological and neurovascular mechanisms that affect the eye, primarily by (1) impaired venolymphatic drainage of the eye and brain due to compression of the internal jugular veins, and (2) ocular dysautonomia from a disruption of the parasympathetic/sympathetic system balance, partly due to vagus nerve degeneration. Potential mechanisms, diagnostics, and treatment options for visual disorders initiated by cervical structural dysfunction are discussed, providing a foundation for future research aimed at improving clinical outcomes for some eye conditions which have an otherwise unknown etiology.

摘要

眼部和视觉症状在年轻人中越来越普遍,同时还出现了文本颈和计算机视觉综合征等情况,尽管其潜在机制尚未完全阐明。颈椎结构与眼睛之间的联系仍相对未被探索。本文采用基于假设驱动、以文献为基础的证据方法,旨在探讨颈椎结构问题可能是视觉症状和眼部疾病潜在机制的这一假设。探索这一假设的目的是为未来的研究奠定基础,并推进诊断和治疗方案。未进行新的分析。本文为颈椎结构功能障碍(包括寰椎(C1)前移)可导致颈动脉鞘动态受压这一假设奠定了基础,这主要通过以下方式促成影响眼睛的神经和神经血管机制:(1)由于颈内静脉受压导致眼睛和大脑的静脉淋巴引流受损;(2)部分由于迷走神经退变导致副交感神经/交感神经系统平衡被破坏而引起眼部自主神经功能障碍。讨论了由颈椎结构功能障碍引发的视觉障碍的潜在机制、诊断方法和治疗方案,为未来旨在改善某些病因不明的眼部疾病临床结果的研究提供了基础。