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肌萎缩侧索硬化症：血清对组织培养中前角细胞的影响。

Amyotrophic lateral sclerosis: effect of serum on anterior horn cells in tissue culture.

作者信息

Wolfgram F, Myers L

出版信息

Science. 1973 Feb 9;179(4073):579-80. doi: 10.1126/science.179.4073.579.

DOI:10.1126/science.179.4073.579
PMID:4119685
Abstract

A high proportion of diluted serums of patients with amyotrophic lateral sclerosis were toxic to the anterior horn cells of the mouse in tissue culture. This is not a general cytotoxicity, since apparently only the neurons were killed. Serums from other degenerative neurological diseases were inactive.

摘要

在组织培养中，肌萎缩侧索硬化症患者的高比例稀释血清对小鼠前角细胞有毒性。这并非一般的细胞毒性，因为显然只有神经元被杀死。来自其他退行性神经疾病的血清则无活性。

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Amyotrophic lateral sclerosis: effect of serum on anterior horn cells in tissue culture.肌萎缩侧索硬化症：血清对组织培养中前角细胞的影响。
Science. 1973 Feb 9;179(4073):579-80. doi: 10.1126/science.179.4073.579.
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Ann Neurol. 1978 Oct;4(4):384. doi: 10.1002/ana.410040419.

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