Wolfgram F, Myers L
Science. 1973 Feb 9;179(4073):579-80. doi: 10.1126/science.179.4073.579.
A high proportion of diluted serums of patients with amyotrophic lateral sclerosis were toxic to the anterior horn cells of the mouse in tissue culture. This is not a general cytotoxicity, since apparently only the neurons were killed. Serums from other degenerative neurological diseases were inactive.
在组织培养中,肌萎缩侧索硬化症患者的高比例稀释血清对小鼠前角细胞有毒性。这并非一般的细胞毒性,因为显然只有神经元被杀死。来自其他退行性神经疾病的血清则无活性。