Oversohl K, So C S
MMW Munch Med Wochenschr. 1977 Nov 4;119(44):1415-8.
The importance of thrombocyte function in atherogenesis is discussed in the light of experimental and clinical results. Adhesion and aggregation of thrombocytes on an intact or injured artery wall may be the first step to atherosclerotic plaque. In vitro measurements of aggregation, in vivo measurements of thrombocytic survival time and microscopic and histological examinations are all consistent in showing a rise in aggregation of thrombocytes in the early stages of arteriosclerosis. The measurement of thrombocyte function is therefore recommended in addition to the known risk factors in patients with a greater risk of arteriosclerosis.
结合实验和临床结果讨论了血小板功能在动脉粥样硬化形成中的重要性。血小板在完整或受损动脉壁上的黏附和聚集可能是动脉粥样硬化斑块形成的第一步。体外聚集测量、体内血小板存活时间测量以及显微镜和组织学检查均一致表明，在动脉硬化早期血小板聚集增加。因此，对于动脉硬化风险较高的患者，除了已知的风险因素外，建议进行血小板功能检测。
