沙鼠（肥尾沙鼠）胰岛中生物胺的存在（作者译）
[Presence of biogenic amines in the Langerhans' islets of the sand rat (Psammomys obesus) (author's transl)].
作者信息
von Dorsche H H, Titlbach M
出版信息
Acta Histochem. 1977;59(2):264-72.
The islets of Langerhans of sand rats (Psammomys obesus) have been investigated ultrahistochemical in order to demonstrate biogenic amines. It could be found that amine containing vesicles with a diameter of 600 to 700 nm from the type of catecholamine granules exist in A-cells as well as in B-cells. Further, 2 very rare cell types not containing specific hormone granules could be found. These cells contain particles, in one case similar to catecholamine granules and in the other case representing serotonine-like granules according to their electron optical properties. It can be stated that the sand-rat belongs to the species containing amines in A- and B-cells. Moreover they contain 2 amines simultaneously. The importance of the amines for the regulation of the hormone secretion of the islets of Langerhans is discussed and the connections to the diabetes mellitus are refered to.
为了证实生物胺的存在，对沙鼠（肥胖沙鼠）的胰岛进行了超组织化学研究。结果发现，直径为600至700纳米的含胺小泡，其类型为儿茶酚胺颗粒，存在于A细胞和B细胞中。此外，还发现了2种非常罕见的不含特定激素颗粒的细胞类型。根据其电子光学特性，这些细胞含有颗粒，在一种情况下类似于儿茶酚胺颗粒，在另一种情况下代表类血清素颗粒。可以说，沙鼠属于在A细胞和B细胞中含有胺类的物种。此外，它们同时含有2种胺类。文中讨论了胺类对胰岛激素分泌调节的重要性，并提及了与糖尿病的联系。
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