Cheng V S, Wang C C
Cancer. 1977 Dec;40(6):3038-41. doi: 10.1002/1097-0142(197712)40:6<3038::aid-cncr2820400641>3.0.co;2-9.
The therapy records of 66 patients with carcinomas of the paranasal sinuses were reviewed; primary carcinomas occurred in the maxillary sinus in 50 patients, the ethmoid sinus in 11 patients, the sphenoid sinus in 4 patients and the frontal sinus in 1 patient. The tumors of the maxillary sinus were staged retrospectively according to the American Joint Committee staging system recommended in 1976; 1 of 2 patients with T1, 5 of 11 patients with T2, 10 of 34 patients with T3 and 1 of 3 patients with T4 lesions showed no evidence of disease (NED) at 3 years. Combined high dose irradiation (6,000 rads in 6 weeks) followed by radical surgery in 4 to 6 weeks was well tolerated; this approach is recommended for the treatment of T1, T2, and selected T3-4 maxillary sinus lesions. Only 2 of 11 patients with ethmoid sinus lesions survived at 3 years.
回顾了66例鼻窦癌患者的治疗记录；其中50例原发癌发生在上颌窦，11例发生在筛窦，4例发生在蝶窦，1例发生在额窦。上颌窦肿瘤根据1976年推荐的美国联合委员会分期系统进行回顾性分期；2例T1期患者中有1例、11例T2期患者中有5例、34例T3期患者中有10例以及3例T4期患者中有1例在3年时无疾病证据（NED）。先进行大剂量联合放疗（6周内6000拉德），4至6周后进行根治性手术，患者耐受性良好；推荐采用这种方法治疗T1、T2以及部分T3 - 4期上颌窦病变。11例筛窦病变患者中只有2例存活3年。
