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Long-term actions of sulfonylureas on (pro-) insulin biosynthesis and secretion: I. Lack of evidence for a compensatory increase in (pro-) insulin biosynthesis after exposure of isolated pancreatic rat islets to tolbutamide and glibenclamide in vitro.

作者信息

Schatz H, Steinle D, Pfeiffer E F

出版信息

Horm Metab Res. 1977 Nov;9(6):457-65. doi: 10.1055/s-0028-1093500.

DOI:10.1055/s-0028-1093500
PMID:412764
Abstract
摘要

相似文献

1
Long-term actions of sulfonylureas on (pro-) insulin biosynthesis and secretion: I. Lack of evidence for a compensatory increase in (pro-) insulin biosynthesis after exposure of isolated pancreatic rat islets to tolbutamide and glibenclamide in vitro.
Horm Metab Res. 1977 Nov;9(6):457-65. doi: 10.1055/s-0028-1093500.
2
Long-term actions of sulfonylureas on (pro-)insulin biosynthesis and secretion. II. Studies after administration of tolbutamide and glibenclamide to rats in vivo.
Horm Metab Res. 1978 Jan;10(1):23-9. doi: 10.1055/s-0028-1093474.
3
Long-term actions of sulfonylureas on (Pro-) insulin biosynthesis and secretion. III. Functional state of isolated pancreatic rat islets after culture in the presence of tolbutamide and glibenclamide.磺酰脲类药物对（前）胰岛素生物合成及分泌的长期作用。III. 在甲苯磺丁脲和格列本脲存在的情况下培养后分离的大鼠胰岛的功能状态。
Horm Metab Res. 1981 Jul;13(7):411-2. doi: 10.1055/s-2007-1019284.
4
The effect of tolbutamide and glibenclamide on the incorporation of ( 3 H)leucine and on the conversion of proinsulin to insulin in isolated pancreatic islets.甲苯磺丁脲和格列本脲对分离的胰岛中（3H）亮氨酸掺入及胰岛素原向胰岛素转化的影响。
FEBS Lett. 1972 Oct 1;26(1):237-40. doi: 10.1016/0014-5793(72)80581-7.
5
Insulin release by tolbutamide and glibenclamide. A comparative study on the perfused rat pancreas.甲苯磺丁脲和格列本脲对胰岛素释放的影响。对灌注大鼠胰腺的比较研究。
Naunyn Schmiedebergs Arch Pharmacol. 1979 Apr;306(3):185-8. doi: 10.1007/BF00507101.
6
(Pro-) insulin biosynthesis and release of newly synthesized (pro-) insulin from isolated islets of rat pancreas in the presence of amino acids and sulphonylureas.（前）胰岛素的生物合成以及在氨基酸和磺脲类药物存在的情况下，从大鼠胰腺分离胰岛中释放新合成的（前）胰岛素。
Eur J Clin Invest. 1975 Nov 21;5(6):477-85. doi: 10.1111/j.1365-2362.1975.tb00480.x.
7
Glyburide and tolbutamide induce desensitization of insulin release in rat pancreatic islets by different mechanisms.格列本脲和甲苯磺丁脲通过不同机制诱导大鼠胰岛胰岛素释放脱敏。
Endocrinology. 1992 Oct;131(4):1815-20. doi: 10.1210/endo.131.4.1396327.
8
Chronic exposure to glibenclamide impairs insulin secretion in isolated rat pancreatic islets.长期暴露于格列本脲会损害分离的大鼠胰岛中的胰岛素分泌。
J Endocrinol Invest. 1991 Apr;14(4):287-91. doi: 10.1007/BF03346813.
9
[Long term in vivo and in vitro effect of sulfonylurea compounds on the islands of Langerhans of rat pancreas. Existence of a feedback mechanism between storage and synthesis apparatus of beta cells].[磺酰脲类化合物对大鼠胰腺朗格汉斯岛的长期体内外作用。β细胞储存与合成装置之间反馈机制的存在]
Verh Dtsch Ges Inn Med. 1977;83:1378-84.
10
Stimulation of insulin secretion from isolated rat islets by SaRI 59-801.SaRI 59 - 801对分离的大鼠胰岛胰岛素分泌的刺激作用。
Diabetes. 1985 Jun;34(6):548-52. doi: 10.2337/diab.34.6.548.

引用本文的文献

1
Blocking Kir6.2 channels with SpTx1 potentiates glucose-stimulated insulin secretion from murine pancreatic β cells and lowers blood glucose in diabetic mice.SpTx1 阻断 Kir6.2 通道可增强小鼠胰岛 β 细胞的葡萄糖刺激胰岛素分泌并降低糖尿病小鼠的血糖。
Elife. 2022 Feb 25;11:e77026. doi: 10.7554/eLife.77026.
2
Insulin secretion and (pro)insulin biosynthesis of cultured mice islets after glibenclamide loading in vitro.体外给予格列本脲后培养的小鼠胰岛的胰岛素分泌及（前）胰岛素生物合成
Experientia. 1980 Apr 15;36(4):467-8. doi: 10.1007/BF01975151.
3
Long-term gliclazide treatment improves the in vitro glucose-induced insulin release in rats with type 2 (non-insulin-dependent) diabetes induced by neonatal streptozotocin.
长期使用格列齐特治疗可改善新生链脲佐菌素诱导的2型（非胰岛素依赖型）糖尿病大鼠体外葡萄糖诱导的胰岛素释放。
Diabetologia. 1989 Aug;32(8):577-84. doi: 10.1007/BF00285331.